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WO/2017/162390A1 |
New benzenesulfonyl asymmetric ureas are herein disclosed, corresponding to the general formulas (I) –(IV) and pharmaceutically acceptable salts thereof, whose structure and substituents are detailed in the specification. Procedures fo...
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WO/2017/153235A1 |
The invention relates to novel substituted N-cyclo-3-aryl-1-naphthamide derivatives, to methods for producing same, to the use thereof, either alone or in combination, for the treatment and/or prevention of diseases, and to their use for...
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WO/2017/150478A1 |
[Problem] To provide an industrially preferred method for producing a sulfoxide derivative. [Solution] A method for producing a sulfoxide derivative represented by general formula (1), the method being characterized in that a sulfide der...
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WO/2017/137147A1 |
The present invention relates to novel crystalline modifications of N-(4,5- bismethanesulfonyl-2-methylbenzoyl)guanidine hydrochloride, novel N-(4,5- bismethanesulfonyl-2-methylbenzoyl)guanidine salts and their crystalline modifications ...
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WO/2017/135293A1 |
The purpose of the present invention is to provide a solar cell which exhibits excellent photoelectric conversion efficiency, and in which a decrease in photoelectric conversion efficiency caused by continuous exposure to light (photodeg...
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WO/2017/129818A1 |
The invention relates to a method for purifying peptides which are produced by solid phase peptide synthesis (SPPS) and corresponding linker molecules for use in said method.
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WO/2017/131221A1 |
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4a and R4b are as defined in the specification, processes for their preparation, pharmaceutical compositions cont...
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WO/2017/130798A1 |
Disclosed is a polyarylene sulfide resin having a main chain including a structural unit represented by general formula (1.1). No absorption peak derived from the S=O stretching vibration of a sulfonyl group is observed in the infrared a...
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WO/2017/109178A1 |
A subject of the present invention is the use of a compound having the general formula (I): (I) wherein V, W, X4, X5, X6, X7, X'4, X'5, X'6, X'7, Y, Y', R3, R'3, R4 and R'4 are as defined in any one of claims 1 to 11, for the detection, ...
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WO/2017/102706A1 |
Processes for reducing the amount of a gaseous iodide-containing impurity present in a recycle gas stream used in the production of ethylene oxide, in particular alkyl iodide and vinyl iodide impurities, are provided. Processes for produ...
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WO/2017/098900A1 |
The present invention is a method for purifying dimethyl sulfoxide, comprising distilling a dimethyl sulfoxide-containing liquid in an inert gas atmosphere in the presence of sodium carbonate to distil out dimethyl sulfoxide, wherein the...
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WO/2017/092446A1 |
A herbicidal composition is provided, the composition comprising: (A) the crystalline modification I of 2-(4-mesyl-2-nitrobenzoyl)cyclohexane-1,3-dione (mesotrione); and (B) the crystalline modification I of methyl 3-(4-methoxy-6-methyl-...
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WO/2017/093172A1 |
Disclosed is a method for producing 2-alkyl-4-trifluoromethyl-3-alkyl sulfonyl benzoic acids of formula (I). In said formula, the substituents represent groups such as alkyl and substituted phenyl.
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WO/2017/091279A1 |
Methods for preparing isotopically modified 1,4-diene systems from non- isotopically modified 1,4-dienes involve selective oxidation of one or more bis-allylic position(s), or the preparation of isotopically modified 1,4-diene systems vi...
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WO/2017/086302A1 |
According to the present invention, the contained amount of a compound measured by mass spectrometry to have a molecular weight of 650-670, typically a molecular weight of 660, is reduced to 0.5 mass% or less in a heat-sensitive recordin...
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WO/2017/073468A1 |
A compound represented by formula (3) (wherein R1 represents a C1-C6 alkyl group which may have at least one halogen atom; R2 represents a C1-C6 alkyl group; and m represents an integer of 0 to 3) can be produced by reacting a C1-C6 alka...
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WO/2017/067500A1 |
The invention relates to the field of mite killers, and specifically, to a biphenyl compound and application thereof. The structure is expressed by formula I, and each substituent in the formula is defined in the specification. The formu...
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WO/2017/064910A1 |
The present invention is a method for preventing the decomposition of dimethyl sulfoxide, said method comprising adding sodium carbonate in an amount of 0.0005 to 2 g relative to 100 g of dimethyl sulfoxide contained in a dimethyl sulfox...
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WO/2017/057460A1 |
Provided is a method for producing an organic compound, wherein the organic compound is an industrially useful compound, and a deodorization step, for removing from a reaction solution odorants that are generated in or remaining after a ...
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WO/2017/058716A1 |
Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers or congenital diseases. Specific cancers and congenital disease includes those that are mediated by YAP/TAZ.
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WO/2017/059040A1 |
Disclosed are processes for the preparation of Apremilast and intermediates for its preparation.
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WO/2017/046459A1 |
The invention relates to the use as solvent of a compound including at least one sulfoxide and/or sulfone function and at least one amide function.
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WO/2017/048156A1 |
The invention relates to the field of organic chemistry and medicine, and more particularly to a method of producing synthetic biologically active derivatives of carbopentoxysulphanilic acid. The present method of producing a sodium salt...
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WO/2017/045931A1 |
The present invention relates to compounds according to formula (I) and to heat-curable resin compositions based on polymaleimide resin systems comprising such compounds as co-monomers:, (I) wherein Dis an x-functional group; and x is an...
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WO/2017/036405A1 |
A compound having a chemical structure of formula I, wherein n is 0 or 1, X is N or C-R1, R1 is H or Cl, R2 and R3 are independently H, a halogen or an alkyl group, Ar is a substituted or unsubstituted phenylene or naphthylene group, wit...
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WO/2017/023912A1 |
Compounds according to Formula (I) are provided and salts thereof, wherein R1, R2, R 3 , R4, R5, R6, R13, A, X and Y are as defined herein. Methods for preparing compounds of Formula (I) are also provided, as well as methods of treating ...
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WO/2017/023192A1 |
The invention relates to a group of novel extractants for extracting nitric acid from aqueous solutions, inter alia, wastewater, which extractants can be used for the liquid-liquid extraction of nitric acid and the separation of hydrochl...
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WO/2017/014214A1 |
A compound represented by formula (4) can be produced by adding a heterogeneous transition metal catalyst to a solution containing a compound represented by formula (3) and then subjecting the resultant mixture to a reduction reaction, w...
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WO/2017/013375A1 |
The invention relates to a process for preparing ionomers of unipolar cationic conductivity from fluorine-containing ionic monomers, to said ionomers of unipolar cationic conductivity, to their uses, to an electrolytic composition compri...
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WO/2017/010399A1 |
Provided are compounds having RORγt inhibitory effects represented by formula (I). Compounds represented by formula (I) (wherein L represents -NR1ACO-, -SO2- or the like, A represents a substituted or unsubstituted aromatic carbocyclic ...
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WO/2016/205707A1 |
Disclosed herein are novel cannabionid receptor-2 (CB2) agonists and inverse agonists represented by Formula (I), and method of modulating the activity of CB2 by contacting the CB-2 receptor with a compound of Formula (I). Also, disclose...
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WO/2016/197900A1 |
A process for the preparation of mesotrione enolate is provided, the process comprising providing a solution of mesotrione in an organic solvent and contacting the solution with a moderate base in the presence of water at a pH of from 6 ...
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WO/2016/198374A1 |
Substituted aromatic sulfonamides of formula (I) pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a di...
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WO/2016/201039A1 |
A process for preparing diaryl sulfones, such as 4,4'-dichlorodiphenylsulfone is disclosed. The process comprises contacting an aryl compound with sulfur trioxide to provide a benzene sulfonic acid. The benzene sulfonic acid is coupled t...
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WO/2016/191872A1 |
Methods and compositions are provided for the treatment of familial exudative vitreoretinopathy (FEVR) through the administration of a therapeutically effective amount of a sphingosine-1-phosphate receptor type 2 (S1PR2) antagonist. Also...
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WO/2016/193452A1 |
The present invention relates to compounds according to Formula I: or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORy and are useful for the treatment of RORy mediated diseases.
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WO/2016/193470A1 |
The present invention relates to compounds according to Formula (I): or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORy and are useful for the treatment of RORy mediated diseases.
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WO/2016/192694A1 |
The invention relates to a preparation method of (S)-l-(3-ethoxy-4-methoxyphenyl)- 2-(methylsulfonyl)-ethyl-amine (S)-l, or its N-acyl derivatives of general formula (S)-2. The amine (S)-l is the key intermediate in the synthesis of (S)-...
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WO/2016/194929A1 |
Compounds shown by formula (3): (in the formula, R1 represents a C1-C6 perfluoroalkyl group, R2 represents a C1-C6 alkyl group, and m represents any integer of 0-3) or salts thereof which are useful as production intermediates of pharmac...
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WO/2016/196664A1 |
The invention provides methods and agents that modulate RelA activity. These methods and modulators of RelA acitivity can be used to treat cancer progression of basal-like breast cancer, such as triple-negative breast cancer.
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WO/2016/196591A1 |
Small molecule compounds derived from α-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB,...
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WO/2016/193459A1 |
The present invention relates to compounds according to Formula I: or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORy and are useful for the treatment of RORy mediated diseases such as autoimmu...
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WO/2016/193461A1 |
The present invention relates to novel compounds according to Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORγ and are useful for the treatment of RORγ mediated diseases.
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WO/2016/189486A1 |
The present invention provides an improved process for preparation of an intermediate of apremilast. The present invention also provides an improved process for preparation of apremilast. This invention also provides novel polymorphs of ...
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WO/2016/182021A1 |
In the production of produce, such as agriculture and horticulture, damage caused by disease and the like is greater than ever, and there is a need for the development of a novel horticultural fungicide due to factors such as the outbrea...
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WO/2016/182036A1 |
The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of inflammatory disease and/or central nervous system disease or diseases such as chemot...
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WO/2016/175128A1 |
The present invention relates to a process for producing an allyl-substituted bisphenol compound, the process including a step in which a diallyl-etherified bisphenol compound represented by general formula (I) is caused to undergo therm...
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WO/2016/173020A1 |
A conjugated compound containing a diphenyl sulfone phenyl structure, a method for preparing same, and use for fabricating a light emitting layer or an electronic transmission layer of an organic electroluminescent diode. The compound ha...
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WO/2016/174685A1 |
A process for the resolution of racemic 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylami
ne using novel chiral salts is disclosed. An L-phenylalanine p-toluene-sulfonamide salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsul...
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WO/2016/168059A1 |
This disclosure relates to the field of moiecuies having pesticida i utility against pests in Phyla Arthropoda, Moliusca, and hJematoda, processes to produce such moiecuies, intermediates used In such processes, pesticidai compositions c...
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