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WO/2023/167325A1 |
The present invention addresses the problem of developing a metal catalyst which is suitable for continuous flow organic synthesis reaction, is excellent in durability, and has high activity. The present invention provides an immobiliz...
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WO/2023/160035A1 |
A β-elemene vinylation coupled derivative, and a preparation method therefor and the use thereof in the preparation of an antitumor drug. Provided are a β-elemene vinylation coupled derivative having a structure as represented by formu...
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WO/2023/160316A1 |
Disclosed are a pyrethroid compound containing double bonds and cyano groups, a synthesis method therefor and an application thereof. In the synthesis method, 3-formyl-2,2-dimethyl-cyclopropanoate t-butyl ester and cyanomethylphosphonate...
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WO/2023/163067A1 |
A catalyst containing: metal oxides, which are oxides of metals including molybdenum, bismuth and iron; and silica for supporting the metal oxides, wherein A/B is 0.95 to 1.04 where A is a silicon surface parameter based on SEM-EDX, and ...
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WO/2023/159303A1 |
Provided herein are Myc-Max inhibitory compounds having the structure of Formula I or Formula II and compositions thereof for use in the treatment of cancer. In particular, the Myc- Max inhibitory compounds may be useful for the treatmen...
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WO/2023/157862A1 |
Provided is a method for producing α-fluoroether starting from an inactivated chloride. Disclosed is a method for producing a compound represented by formula (3), the method comprising step A in which a compound represented by formula (...
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WO/2023/156986A1 |
The present disclosure relates to a process for the preparation of nitrile herbicides, their esters and salts. The process of the present disclosure provides nitrile herbicides, their esters and salts with high purity and in greater yiel...
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WO/2023/149548A1 |
The present invention addresses the problem of providing a novel pharmaceutical composition, and in particular, a novel anti-cancer pharmaceutical composition, and a novel compound used in said pharmaceutical composition. The present i...
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WO/2023/148215A1 |
The invention is directed to a compound of formula (I) for use in organic electronic devices, an organic semiconductor layer comprising the compound of formula (I), an organic electronic device comprising the organic semiconductor layer,...
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WO/2023/149559A1 |
[Problem] The present invention provides a catalyst for hydrogenation reactions, the catalyst having excellent catalyst durability and being capable of selectively hydrogenating only some functional groups and/or unsaturated bonds of an ...
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WO/2023/143601A1 |
Provided in the present invention are a novel cationic lipid, a lipid nanoparticle and a nucleic acid vaccine. In the present invention, a specific cationic lipid is selected for preparing a lipid nanoparticle mRNA vaccine, which is foun...
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WO/2023/146513A1 |
Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating diseases. Specific diseases include those that are mediated by YAP/TAZ or those that are modulated by the interaction be...
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WO/2023/143600A1 |
The present invention provides a novel cationic lipid, a lipid nanoparticle, and a nucleic acid vaccine. According to the present invention, a specific cationic lipid is selected to prepare a lipid nanoparticle mRNA vaccine, and the lipi...
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WO/2023/143591A1 |
The present invention provides a novel cationic lipid, a lipid nanoparticle and a nucleic acid vaccine. It is found that the lipid nanoparticle mRNA vaccine prepared in the present invention by selecting a specific cationic lipid has bet...
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WO/2023/142460A1 |
The present invention discloses a method for synthesizing aryl phenol by means of a reaction between an aryl halide and a phenol compound under the induction of visible light, which method comprises: under the protection of an inert gas,...
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WO/2023/142492A1 |
The present application relates to the field of organic light-emitting materials, and in particular to an organic compound, an electronic component, and an electronic device. The structure of the organic compound is as represented by for...
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WO/2023/139597A1 |
The present invention discloses a process for extractive distillation for separating one or more hydrocarbons from a gaseous mixture. Briefly, the process disclosed in the present invention provide a process for separation of propylene f...
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WO/2023/135599A1 |
The present invention relates to an improved process for the industrial-scale production process of Tau-fluvalinate in a purified form comprising optimization of the reaction conditions by timely acid neutralization, resulting in prevent...
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WO/2023/131729A1 |
The present invention relates to a process for preparing electron-deficient olefin monomers. The process is a direct synthesis of electron-deficient monomers by catalysing a reaction between an active methylene compound and a mixture of ...
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WO/2023/128638A1 |
The present invention relates to an anthracene derivative compound having a characteristic structure in which an aliphatic aromatic mixed ring group is substituted, and to an organic light-emitting device comprising same. The present inv...
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WO/2023/122572A1 |
A process for producing acetonitrile, the process comprising dehydrating a feedstock stream comprising acetonitrile, acrylonitrile, allyl alcohol, and water (and optionally methanol) in a dehydration (first) column to yield a dehydrated ...
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WO/2023/122276A1 |
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the compounds, and methods of using the compounds and compositions comprising the c...
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WO/2023/118376A1 |
The invention concerns a process for recovering acetonitrile from an acetonitrile stream consisting of acetonitrile, 16 to 90 weight percent water, low boiling impurities having a boiling point below the boiling point of acetonitrile/wat...
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WO/2023/108601A1 |
A synthesis method for loxoprofen and analogues thereof as shown in the following reaction formula, wherein compound (I) undergoes a reaction under the catalysis of a catalyst to generate compound (II). The method avoids the use of a lar...
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WO/2023/112813A1 |
This fluorine-containing ether compound is represented by the following formula. R1-R2-CH2-R3a-CH2-R4a-CH2-R3b-CH2-R4b-CH2-R3c -CH2-R5-R6 (R3a, R3b, and R3c each represent a perfluoropolyether chain; R2, R4a, R4b, and R5 each represent a...
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WO/2023/112722A1 |
The present invention addresses the problem of providing: a compound suitably used for forming an optical anisotropic membrane that has excellent reverse wavelength dispersion property and moist heat durability; a polymerizable compositi...
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WO/2023/105430A1 |
The present invention concerns processes for producing acrylonitrile from glycerol, comprising a dehydration step to produce acrolein and an ammoxidation step to produce acrylonitrile. The process comprises the recycling of one or more g...
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WO/2023/103261A1 |
Disclosed in the present invention are a crystal form B of ethyl 2-cyano-3-amino-3-phenylacrylate, a preparation method, and an application. The crystal form B of ethyl 2-cyano-3-amino-3-phenylacrylate provided in the present invention h...
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WO/2023/096387A1 |
The present invention relates to an organic light-emitting compound represented by [chemical formula A] or [chemical formula B], which can be used in an organic light-emitting device, and an organic light-emitting device comprising same,...
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WO/2023/096399A1 |
The present invention relates to an organic light-emitting diode in which a light-emitting layer comprises a compound represented by [chemical formula A] as a host and comprises a compound represented by [chemical formula 3], [chemical f...
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WO/2023/096210A1 |
The present invention provides: a novel compound capable of improving the luminous efficiency, stability and lifespan of an element; an organic electrical element using same; and an electronic device therefor.
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WO/2023/087632A1 |
The present invention belongs to the field of medicinal chemistry, and specifically disclosed are an anti-inflammatory analgesic compound and the use thereof. The compound of the present invention is a compound having a structure shown i...
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WO/2023/090086A1 |
Provided are a secondary monohydrofluoroalkane selective adduct and a method for producing the same. A compound represented by formula (3) is produced by means of a method including a step for reacting a compound represented by formula (...
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WO/2023/082895A1 |
The present invention relates to an organic compound and a use thereof. The organic compound has the structure as shown in formula (1). The compound has a relatively low LUMO energy level, and a prepared red light device has low driving ...
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WO/2023/070483A1 |
The present disclosure provides certain processes of making 3-fluoro-5- (((1R, 2S, 2aS) -1, 2, 3, 3, 4, 4-hexafluoro-2a-hydroxy-2, 2a, 3, 4-tetrahydro-1H-cyclopenta [cd] inden-7-yl) oxy) -benzonitrile and certain polymorphs thereof. Also...
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WO/2023/076626A1 |
The disclosure relates to compounds of Formula (I), which are RXFP1 receptor agonists, compositions containing them, and methods of using them, for example, in the treatment of heart failure, fibrotic diseases, and related diseases such ...
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WO/2023/072670A1 |
The present invention relates to the use of strobilurin type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing an amino acid substitution F129L in the mitochondrial cytochrome b ...
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WO/2023/076532A1 |
The present disclosure provides certain processes of making 3-fluoro-5-(((1R,2S,2aS)- 1,2, 3,3,4, 4-hexafluoro-2a-hydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd
]inden-7-yl)oxy)- benzonitrile and certain polymorphs thereof. Also provided a...
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WO/2023/077040A1 |
The disclosure relates to compounds of Formula (I), which are RXFP1 receptor agonists, compositions containing them, and methods of using them, for example, in the treatment of heart failure, fibrotic diseases, and related diseases such ...
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WO/2023/062922A1 |
The present invention is a polyurethane, the polyurethane being characterized by containing a phenolic hydroxyl group represented by general formula (1A). Provided thereby are an electroconductive paste composition for forming a stretcha...
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WO/2023/060929A1 |
The present invention relates to an application of a polydentate phosphite ligand in the catalytic synthesis of adiponitrile. The ligand is represented by general formula (I). A method for catalytically synthesizing adiponitrile comprise...
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WO/2023/064305A1 |
The present disclosure provides certain processes of making 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,
3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)-benzonitrile
(Compound 1) and certain polymorphs thereof. Also prov...
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WO/2023/060458A1 |
The present disclosure provides certain processes ofmaking 3-fluoro-5- ( ( (1S, 2aR) -1, 3, 3, 4, 4-pentafluoro-2a-hydroxy-2, 2a, 3, 4-tetrahydro-1H-cyclopenta [cd] inden-7-yl) oxy) -benzonitrile (Compound 1) and certain polymorphs there...
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WO/2023/047104A9 |
The invention relates to a process for producing a compound comprising an 18F-difluoromethyl group or a compound comprising an 18F-difluoromethylene group, which process comprises contacting a compound comprising a nucleophilic group wit...
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WO/2023/061999A1 |
The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.
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WO/2023/060431A1 |
Disclosed are certain processes of making 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,
3,4-tetrahydro-1H-cyclopenta [cd] inden-7-yl) oxy)-benzonitrile (Compound 1) and certain polymorphs thereof. Also disclosed are pharma...
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WO/2023/060811A1 |
Disclosed in the present invention are a fluralaner intermediate and a method for preparing fluralaner thereby. The fluralaner intermediate-5 is aaa. A synthetic route comprises: using m-xylene as a starting raw material, performing halo...
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WO/2023/059224A1 |
The invention relates to new biologically active derivatives of substituted 2,3-dihydrofuran-3-ones, which can be used as antiviral agents with a broad spectrum of antiviral activity. The compound represented by Formula (I) is described:...
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WO/2023/052103A1 |
The present invention provides a new compound of formula (I), and a process for producing the compound of formula (I) and a process for producing oxazole compounds by using the compound of formula (I),wherein R is H, or lower alkyl or ar...
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WO/2023/048505A1 |
The present application provides a functional polypeptide variant-albumin conjugate prepared using an APN group-bearing linker. Furthermore, the present application provides an albumin-linker conjugate, prepared using an APN group-bearin...
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