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WO/2015/089271A1 |
A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; R1 and R2 are each independently H; optionally substituted alkyl; optionally subs...
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WO/2015/086698A1 |
The present invention relates to a process for providing dihalogen substituted salicylic acid derivativesof formula (II).
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WO/2015/082938A1 |
The present invention relates to a compound of formula I, or a pharmaceutically acceptable salt thereof : (I) wherein: n is 0 or 1; R1 is selected from H, alkyl and aralkyl, wherein said alkyl and aralkyl groups may be optionally substit...
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WO/2015/082809A1 |
The present invention relates to a particular process for separating a mixture of two linear cyano acids resulting from the oxidative cleavage of an unsaturated fatty acid nitrile, said mixture having a eutectic with a specific compositi...
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WO/2015/080183A1 |
A compound represented by general formula (1) is useful as a light-emitting material. In general formula (1), zero to one of R1 to R5 represents a cyano group, one to five of R1 to R5 independently represent a group represented by genera...
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WO/2015/078802A1 |
The present invention relates to compounds of general formula (I), wherein the groups R1, R2, R3, X, m and n are defined as in claim 1, wich have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate ...
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WO/2015/080221A1 |
[Problem] To provide: a liquid crystal alignment film that can be easily formed, can efficiently impart alignment regulating force at a small amount of polarized irradiation, and exhibits superior liquid crystal molecule alignment and pr...
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WO/2015/079955A1 |
Provided are a solid base catalyst having improved activity, and a method and a reactor relating to the same. This solid base catalyst comprises a carbonized material having nitrogen atoms and boron atoms. This method for producing the s...
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WO/2015/074135A1 |
The present invention relates to a novel family of protein kinase inhibitors, more specifically the present invention is directed to inhibitors of the members of the Tec or Src protein kinase families. The present invention also relates ...
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WO/2015/056663A1 |
The present invention provides a medical drug containing a compound represented by general formula (1), a pharmaceutically acceptable salt thereof, or a solvate of the compound or salt. The following are provided: the compound represente...
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WO/2015/054476A1 |
Methods of halogenating a carbon containing compound having an sp3 C-H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provide...
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WO/2015/054357A1 |
A family of silicone rubbers (e.g., polydimethylsiloxane) carrying one or more cyanoacrylate groups and their methods of production are provided. These silicone rubbers endowed with cyanoacrylate groups are useful in a variety of wound c...
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WO/2015/050236A1 |
The purpose of the present invention is to make possible synthesis of various fluorine-containing compounds having organic groups at both terminals of a tetrafluoroethylene structure (-CF2-CF2-). The present invention provides fluorine-c...
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WO/2015/039172A1 |
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
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WO/2015/040425A1 |
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: Y is –CONR1- or optionally substituted arylene or optionally substituted heteroarylene; R1 is H, Cl, F, CH3 or CF3; 10 each R4 is independently H, CH3 or ...
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WO/2015/032942A1 |
The invention relates to a compound of Formula (I) and its use as a selective dipeptidyl peptidase I inhibitor, as well as pharmaceutical compositions comprising said compound, and methods of treatment involving said compounds.
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WO/2015/027324A1 |
Described herein are a series of compounds having the structure of Formula I for use in the inhibition of MAO and uses thereof for the treatment of a barrier disease, obesity, solid epithelial cell tumor metastasis, diabetes, an auto-imm...
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WO/2015/027773A1 |
The present invention relates to an application of dimethylaminopyridine (DMAP) hydrochloride serving as recyclable catalyst in an acylation reaction (as represented by equation I). The application comprises: dissolving DMAP into a nonpo...
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WO/2015/025960A1 |
Provided are: a compound having high activity against harmful organisms; a harmful organism control agent comprising the compound; and a method for controlling harmful organisms by applying the compound. A phenoxyalkylbenzamide-type comp...
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WO/2015/024978A1 |
The present invention relates to the manufacture and the use of specific organic compounds of formula (II) wherein n is either 1 or 2, and wherein R1 is linear C1-4 alkyl or branched C3-4 alkyl, wherein R2 is hydrogen or linear C1-4 alky...
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WO/2015/014230A1 |
The present invention relates to a matrix metalloproteinase inhibitor and a use thereof. In particular, the matrix metalloproteinase inhibitor has a structure as shown in formula (I) or a pharmaceutically acceptable salt thereof, and can...
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WO/2015/016148A1 |
In the present invention, the method for producing trans-bis(aminomethyl)cyclohexane includes the following: a trans isomerization step of isomerizing cis-dicyanocyclohexane into trans-dicyanocyclohexane by heating dicyanocyclohexane, wh...
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WO/2015/012407A1 |
The present invention pertains to a cellulose acylate film containing a compound having at least one linking group selected from the group consisting of a bivalent linking group represented by -NH-(C=O)-O- and a bivalent linking group re...
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WO/2015/007729A1 |
The present invention relates to industrial process for manufacturing 1,2,3- triylidenetris(cyanomethanylylidene))tris(2,3,5,6-tetrafluor
obenzonitrile)-cyclopropane by oxidizing the precursor methylidenecyclopropene compound (c) with co...
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WO/2015/007630A1 |
The present invention relates to new salts, complexes, crystals, solutions, dispersions, and slurries of threonine-N,N-diacetic acid or derivatives thereof, to formulations containing those, to processes to prepare those, and to the use ...
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WO/2015/009847A1 |
A solvent is at least partially separated from a catalyst. The catalyst comprises nickel and a bidentate phosphorus-containing ligand. The method for separation involves distilling a catalyst solution. The ratio of 2-pentenenitrile to 3-...
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WO/2015/006520A1 |
There are disclosed compounds of Formula (I) that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, suc...
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WO/2015/005298A1 |
The purpose of the present invention is to provide a high purity optically active bicyclic γ-amino acid derivative. The means for accomplishing this purpose is a method for producing a compound represented by general formula (VII), or a...
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WO/2015/006177A1 |
The instant invention relates to pharmaceutical compositions comprising cathespin K inhibitors and Vitamin D. The pharmaceutical compositions of the instant invention include fixed dose combinations of cathepsin K inhibitors with Vitamin...
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WO/2015/001117A1 |
The present invention relates to a process for labeling compounds comprising thiol moieties with 3-arylpropiolonitrile compounds, to 3-arylpropiolonitrile compounds substituted with tag moieties and to specific 3-arylpropiolonitrile link...
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WO/2014/208484A1 |
[Problem] To provide: a novel naphthalocyanine compound which has intense absorption in a near-infrared region and extremely small absorption of a visible light region, and has high durability and good solubility in organic solvents and ...
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WO/2014/210191A1 |
The present invention provides an improved process for preferentially concentrating 2-methylglutaronitrile from mixtures comprising 2-methyl-glutaronitrile and other C6 nitriles having very close relative volatilities, for example, 2-eth...
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WO/2014/203855A2 |
[Problem] The objective of the present invention is to provide an economically advantageous and industrially suitable method for manufacturing a 2-amino-2-hydroxyimino-N-alkoxy acetoimidoyl cyanide represented by general formula (3). [So...
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WO/2014/205337A1 |
Disclosed herein are methods for recovering diphosphonite-containing compounds from mixtures comprising organic mononitriles and organic dinitriles, using liquid-liquid extraction. Also disclosed are treatments to enhance extractability ...
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WO/2014/205195A1 |
Disclosed herein are methods for recovering diphosphonite-containing compounds from mixtures comprising organic mononitriles and organic dinitriles, using liquid-liquid extraction. Also disclosed are treatments to enhance extractability ...
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WO/2014/202765A1 |
The present invention provides an asymmetric and economic synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine via novel intermediates applying an asymmetric enzymatic, biomimetic or catalytic reduction. The present inve...
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WO/2014/199960A1 |
The present invention provides a novel compound represented by formula (IA) or a pharmaceutically acceptable salt thereof, which is useful for prophylaxis or treatment of diseases such as schizophrenia, Alzheimer's disease, cognitive imp...
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WO/2014/200094A1 |
[Problem] To provide a novel production method for a stereoselective, optically active alcohol compound. [Solution] From the compound represented by formula (3), the optically active alcohol compound represented by formula (8) can be pro...
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WO/2014/198880A1 |
The invention provides a compound of formula (I) wherein R2-R10 represent different meanings, and pharmaceutically acceptable salts thereof. The invention also provides synthetic procedures for preparing the compounds of formula (I), pha...
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WO/2014/195253A1 |
Primarily, the present invention relates to the use of substances of the formula (I) as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for infl...
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WO/2014/195493A1 |
The present invention relates to a method for synthesizing a nitrile/fatty ester aldehyde, including the following steps: 1) hydroformylating a nitrile/ester/ω unsaturated fatty acid substrate under specific partial pressure, temperatur...
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WO/2014/191292A1 |
The present invention relates to novel compounds that are particularly useful for the alignment, especially photoalignment, of slave material, especially liquid crystals for optical or electro-optical applications, such as security appli...
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WO/2014/190237A1 |
Compounds and methods for preparing substituted 3-(l -amino-2-methylpentane-3-yl)phenyl compounds from an isomerically pure starting material are described. In particular, methods of preparing a 3-(l-(dimethylamino)-2-methylpentane-3-yl)...
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WO/2014/186981A1 |
The present invention provides a method for preparing o(p)-hydroxybenzonitrile. o(p)-hydroxybenzonitrile is an important fine chemical intermediate used in the fields of medicine and pesticide. In the present invention, o(p)-halogenated ...
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WO/2014/184235A1 |
Compounds of formula I, pharmaceutically acceptable salts thereof, diastereomers, enantiomers, or mixtures thereof: wherein R, X, Y, Z, n and A are as defined in the specification, as well as pharmaceutical compositions including the com...
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WO/2014/175267A1 |
The purpose of the invention is to provide a novel organometallic compound that can be utilized as a catalyst having high generality, high activity, and excellent functional group selectivity. The invention pertains to a novel organometa...
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WO/2014/173044A1 |
Disclosed is a method for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine. First, 3-cyano-3,5,5-trimethylcyclohexanone reacts with ammonia to generate 3-cyano-3,5,5-trimethylcyclohexylimine, the 3-cyano-3,5,5-trimethylcyclohexylim...
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WO/2014/168260A1 |
This composition for forming an optically anisotropic layer contains a polymerizable liquid crystal compound, a photoinitiator, and an ester solvent having a boiling point of 120-200°C and a vapor pressure of no greater than 0.7 kPa.
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WO/2014/161850A1 |
The present invention provides a novel and improved process for the production of the production of hindered anilines containing perfluoroalky groups in good yield any by using close to stoichiometric amounts of acylating agent.
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WO/2014/159802A1 |
The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulator...
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