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WO/2022/268145A1 |
The present disclosure relates to an amide compound as represented by general formula I, or a prodrug, a pharmaceutically acceptable salt, a complex or a solvate thereof. The compound of the present disclosure has a new structure and has...
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WO/2022/264037A1 |
The present disclosure provides compounds represented by Formula I: I, and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, and R3 are as defined as set forth in the specification. The present disclosure also p...
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WO/2022/263244A1 |
The present invention relates to the use of quaternized betaines in a specific manner as a fuel additive, such as, more particularly, as a deposit control additive; for reducing the level of or preventing deposits in the injection system...
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WO/2022/263525A1 |
The present invention is directed at organic ammonium salts comprising an organic ammonium-group-comprising cation which does not contain an estolide moiety and a carboxylate anion (COO-) group-comprising anion selected from the group co...
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WO/2022/258792A1 |
The present invention relates to new cinnamic add amides which may be used for treatment of fibrosis and neoplasia and to cinnamic acid amides for use in the treatment of fibrosis, neoplasia, arthrolithiasis, familiar mediterranean fever...
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WO/2022/261635A1 |
A surfactant composition includes a homogeneous mixture of greater than 70%, by weight, of N-acyl alaninate surfactant of formula (I) and an N-acyl amino acid surfactant of formula (II). A process for preparation of a blend of an N-acyl ...
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WO/2022/255778A1 |
The present invention relates to a method for screening for a compound that binds to human IL-33 protein and inhibits IL-33, a composition for inhibiting IL-33 protein, comprising a compound selected through screening, and a pharmaceutic...
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WO/2022/247755A1 |
Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol andpolymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucl...
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WO/2022/249994A1 |
This method for producing N-(hetero)aryl(meth)acrylamide compounds comprises obtaining a compound given by general formula (3) by carrying out an amidation reaction, at a temperature above 120°C, between a compound given by general form...
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WO/2022/240744A1 |
An organoclay composition exchanged with a ester quaternary ammonium ion or amide quaternary ammonium ion or a glycine betaine residue.
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WO/2022/237485A1 |
The present invention mainly relates to the field of organic synthesis, and disclosed is a continuous synthesis process of 2-acetamido-5-nitroanisole. In the process, a microchannel continuous flow reactor is used as a main reaction devi...
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WO/2022/237904A1 |
A naphthalene ring-containing compound, a pharmaceutical composition containing same, and the use thereof. A naphthalene ring-containing compound as represented by formula III, a pharmaceutically acceptable salt thereof, a solvate thereo...
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WO/2022/233309A1 |
Disclosed in the present invention are a 150-cavity-targeted Oseltamivir derivative, a preparation method therefor, and an application thereof. The derivative has a structure represented by general formula I or II. Also disclosed in the ...
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WO/2022/232509A1 |
Described herein are, inter alia, methods of treating cancer using an EGFR-TK inhibitor and a PCNA inhibitor, and pharmaceutical compositions comprising an EGFR-TK inhibitor and a PCNA inhibitor.
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WO/2022/232366A1 |
Described herein are novel reduction reactions. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticide...
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WO/2022/226416A1 |
The present disclosure provides photo-polymerizable monomers, photo-curable resins comprising one or more of such monomers, as well as polymeric materials formed from the photo-curable resins. Further provided herein are methods of produ...
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WO/2022/224274A1 |
The present invention provides polymorphic forms namely crystalline Form I, amorphous form and amorphous solid dispersions of Sacubitril-Telmisartan. It also provides process for the preparation of the same.
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WO/2022/224968A1 |
The purpose of the present invention is to provide an alkylating agent that efficiently labels a polysulfide having an (S)n structure. This problem can be solved by a functional group of the present invention, which is for labeling a p...
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WO/2022/221689A1 |
Provided herein are nitrophenyl-acrylamide compounds, their preparation, and uses thereof.
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WO/2022/213195A1 |
There is provided compounds of formula (I) or a pharmaceutically acceptable salt thereof, which are melatonin MT2 agonists, as well as pharmaceutical compositions comprising such compounds. The invention also provides the use of the comp...
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WO/2022/211812A1 |
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present i...
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WO/2022/208545A1 |
The present invention discloses a process for the hydrogenation of imines of Formula I by palladium-based catalyst to provide product of Formula II with more than 95% conversion of substrate and more than 95% of desired hydrogenated prod...
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WO/2022/202888A1 |
The purpose of the present disclosure is to provide a method for producing organic fluorine compounds that enables the thorough removal of sulfur-containing substances, or to provide an organic fluorine compound-containing composition th...
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WO/2022/204080A1 |
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...
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WO/2022/204288A1 |
The disclosure features novel lipids and compositions involving the same. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. ...
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WO/2022/195288A1 |
The invention relates to a process for preparing an N-acylethanolamide derivative.
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WO/2022/198139A1 |
The present disclosure relates to compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof. The present disclosure also relates to uses of the compounds, e.g., in treating or preventing diseases, disorders, or condition...
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WO/2022/196860A1 |
The present invention relates to a method for manufacturing a temperature- and stress-sensitive film, and a temperature and stress measurement system and, more specifically, to: manufacturing a flexible temperature- and stress-sensitive ...
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WO/2022/197681A1 |
Disclosed herein are salts of the compound of Formula (I) and polymorphs thereof, methods of making the same, and their methods of use in treating eye diseases and disorders, particularly those associated with inflammation and/or vascula...
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WO/2022/188501A1 |
The present disclosure relates to the technical field of resource reutilization, and provides a recycling method for degraded waste of an acetyl Meldrum's acid derivative. According to the present disclosure, the degraded waste of the ac...
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WO/2022/189190A1 |
The invention relates to compounds of formula (I), and their use as herbicides. In said formula, R1 to R8 represent groups such as hydrogen, halogen or organic groups such as alkyl, alkenyl, alkynyl, or alkoxy; X is a bond or a divalent ...
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WO/2022/188302A1 |
Disclosed are a pregabalin artificial hapten and a pregabalin artificial antigen, preparation methods therefor, and applications thereof. The molecular structural formula of the pregabalin artificial hapten is as shown in formula (I), an...
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WO/2022/183762A1 |
Disclosed are an anti-phenacetin monoclonal antibody hybridoma cell strain AD, and a preparation method therefor and the use thereof, which relate to the technical field of food safety and immunological detection. The deposit name of the...
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WO/2022/183281A1 |
Among other things, in general, compositions and methods of treatment for muscular dystrophy and other diseases are disclosed. A method of treatment of a subject is disclosed, in which fatty acid utilization is improved. The method inclu...
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WO/2022/180638A1 |
The present invention provides additive compound for warm mix asphalt (WMA) for the paving of road surfaces, whereby the additive compounds facilitate the mixing, lay down and compaction of asphalt mixes at low temperatures while retaini...
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WO/2022/178440A1 |
Provided herein are novel compounds of Formula (I): wherein R1 is selected from the group of C1-C20 alkyl, -CH2-CH2-CH2-NH-C(=O)-C=C, and -CH2-CH2-CH2-N(CH3)-C(=O)-C=C; along with compositions comprising them and uses, including as denta...
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WO/2022/169284A1 |
The present invention relates to a novel compound which enables additional hydrogen bonding with amino acids at specific positions of histone acetyltransferase (HAT) p300 through the structural analysis of HAT p300. The novel compound ac...
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WO/2022/157106A1 |
The presently claimed invention relates to a process for the preparation of mono-, di-, tri-, fluoro arylamide or hetroarylamide.
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WO/2022/152705A1 |
Compounds of Formula (I) wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and formula (II) are as defined in the description. Medicaments.
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WO/2022/152109A2 |
Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nuc...
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WO/2022/149462A1 |
A light-absorbing material according to one embodiment of the present disclosure includes a compound represented by formula (1) as a main component. In formula (1): R1 to R30 are independent of each other and include at least one element...
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WO/2022/150314A1 |
The present disclosure is concerned with substituted phenyl and heterocycloalkyl compounds for the treatment of various cancers such as, for example, sarcomas, carcinomas, hematological cancers, solid tumors, breast cancer, cervical canc...
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WO/2022/145923A1 |
The present invention relates to a pharmaceutical composition which is for preventing or treating viral infections and contains a piperlongumine-based compound as an active ingredient. Specifically, the piperlongumine-based compound acco...
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WO/2022/145707A1 |
The present invention provides a novel piperlongumine-based compound, and an immunomodulator and a health functional food for immunomodulation, which comprise the compound or a pharmaceutically acceptable salt or solvate thereof as an ac...
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WO/2022/133594A1 |
The present disclosure relates to methods for the hydroaminoalkylation of an olefin. Such methods can comprise reacting the olefin with a secondary amine in the presence of a catalyst of Formula (I). The present disclosure also relates t...
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WO/2022/133544A1 |
Cannabidiol (CBD) cannabinoids and CBD cannabinoid analogues with, inter alia, antimicrobial activity, synthetic methods for the preparation thereof and medical uses and formulations containing same.
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WO/2022/134287A1 |
The present invention relates to a method for preparing a carboxylic acid ester compound. Under the catalysis of nitrite, an carboxylic acid reacts with an alcohol in air so as to obtain an ester compound; and the alcohol is ethanol, pro...
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WO/2022/140654A1 |
The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts thereof.
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WO/2022/134297A1 |
The present invention relates to a preparation method for a carboxylate ester compound, comprising: under the catalysis of a nitrite ester, reacting carboxylic acid and methanol in air, so as to obtain an ester compound. The preparation ...
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WO/2022/132455A1 |
A composition comprises one or more trimesic acid derivatives of Formula (I) in which R1, R2, and R3 are independently selected from the group consisting of alkyl groups. A polymer composition comprises a composition as described above a...
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