Title:
ULTRA-SENSITIVE ANALYTE DETECTION AND QUANTIFICATION USING CATCH AND RELEASE WITH PROXIMITY DETECTION
Document Type and Number:
WIPO Patent Application WO/2024/059773
Kind Code:
A3
Abstract:
Provided herein is a highly sensitive analyte detection method that involves catch and release of a target analyte coupled with a proximity assay. Target analyte is captured using a capture binding partner and is also bound by detection binding partners thereby forming an analyte-biding partner complex. The complex is immobilized, and unbound reactants are physically removed. Thereafter the complex is released and a proximity assay is performed on the complex in order to detects its presence.
Inventors:
HANSEN CLINTON (US)
WONG WESLEY (US)
WONG WESLEY (US)
Application Number:
PCT/US2023/074276
Publication Date:
April 25, 2024
Filing Date:
September 14, 2023
Export Citation:
Assignee:
CHILDRENS MEDICAL CT CORP (US)
International Classes:
C12Q1/6823; G01N33/569; G01N33/68
Attorney, Agent or Firm:
TREVISAN, Maria A. et al. (US)
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