REUSABLE SERS MOLECULAR TEST DEVICE, AND METHOD USING SAME

WIPO Patent Application WO/2024/066955

A1

Disclosed in the present invention are a reusable SERS (Surface Enhanced Raman Scattering) molecular test device and a method using same. The reusable SERS molecular test device comprises two glass sheets, wherein a noble metal nano film is deposited on the surface of one of the glass sheets to form an SERS substrate, a metal ring is formed by depositing on an edge region of the SERS substrate by means of a coating process, and the metal ring fits with the SERS substrate to form a two-dimensional air chamber; and the other glass sheet, on which molecules under test are adsorbed and immobilized, is placed upside down on the metal ring, the thickness of the layer of the molecules under test being not greater than the thickness of the metal ring. The SERS molecular test device of the present invention can fundamentally prevent the SERS substrate from being irreversibly contaminated by the molecules under test, so that the SERS substrate can be used in a cleaning-free and reusable manner, thereby greatly reducing the usage cost, and provides transformational technology for the practicability of the SERS substrate.

WANG LEI (CN)
WANG XIA (CN)
ZHAO QIULING (CN)
WANG MAORONG (CN)
ZHANG QINGYUE (CN)

PCT/CN2023/116965

April 04, 2024

September 05, 2023

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QINGDAO UNIV OF SCIENCE AND TECHNOLOGY (CN)
UNIV JINAN (CN)

G01N21/65; C23C14/04; C23C14/18; C23C14/24; C23C14/30; C23C14/35

CN115561224A	2023-01-03
CN109440104A	2019-03-08
CN107313046A	2017-11-03
CN109470681A	2019-03-15
CN113670890A	2021-11-19
JP2011033518A	2011-02-17

BEIJING YUNJIA PAIFU INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)

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