RETINAL PIGMENT EPITHELIAL (RPE) CELL-DIRECTED PEROXIDASE-BASED COMPOSITIONS, METHODS, AND SYSTEMS

Title:

RETINAL PIGMENT EPITHELIAL (RPE) CELL-DIRECTED PEROXIDASE-BASED COMPOSITIONS, METHODS, AND SYSTEMS

Document Type and Number:

WIPO Patent Application WO/2024/040072

Kind Code:

A3

Abstract:

Various peroxidases are useful in treating subjects suffering from diseases associated with buildup of bisretinoids. The disclosed peroxidases may also be useful in activating prodrugs. The disclosed peroxidases may be administered as mature proteins or as coding sequences, in the form of expression vectors (as one example viral vectors) or lipid nanoparticles.

Inventors:

GROHN KRIS (US)
MOODY KELSEY (US)
WOLFE AARON (US)

Application Number:

PCT/US2023/072238

Publication Date:

April 25, 2024

Filing Date:

August 15, 2023

Export Citation:

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Assignee:

LYSOCLEAR INC (US)

International Classes:

A61K38/43; C07K14/47; C12N9/16; C12N15/62

Attorney, Agent or Firm:

JONSEN, Matthew D. et al. (US)

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