Title:
RENAL CELL AGGREGATE, AND METHOD FOR PRODUCING RENAL CELL AGGREGATE
Document Type and Number:
WIPO Patent Application WO/2024/095922
Kind Code:
A1
Abstract:
Provided is a renal cell aggregate in which the expression level of a transporter gene is improved. An embodiment of the present invention relates to a renal cell aggregate. The aggregate satisfies at least one of the following conditions: (a) the expression level of the OAT1 gene is at least 1×10-3 (GAPDH ratio); (b) the expression level of the OAT3 gene is at least 1×10-4 (GAPDH ratio); (c) the expression level of the OCT2 gene is at least 1×10-3 (GAPDH ratio); (d) the expression level of the MATE1 gene is at least 1×10-4 (GAPDH ratio); (e) the expression level of the MATE2 gene is at least 1×10-5 (GAPDH ratio); (f) the expression level of the MDR1 gene is at least 1×10-3 (GAPDH ratio); and (g) the expression level of the UART1 gene is at least 1×10-6 (GAPDH ratio).
Inventors:
TAKAHASHI ETSUSHI (JP)
Application Number:
PCT/JP2023/038925
Publication Date:
May 10, 2024
Filing Date:
October 27, 2023
Export Citation:
Assignee:
NIKKISO CO LTD (JP)
International Classes:
C12N5/077
Attorney, Agent or Firm:
ITOH, Atsushi (JP)
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