PROTEIN HAVING NAMPT ACTIVITY, AND METHOD FOR PRODUCING NMN

Title:

PROTEIN HAVING NAMPT ACTIVITY, AND METHOD FOR PRODUCING NMN

Document Type and Number:

WIPO Patent Application WO/2023/210244

Kind Code:

A1

Abstract:

A protein according to the present invention is a protein which is disclosed in any one among [1]-[3], and which has nicotinamide phosphoribosyltransferase activity. [1] A protein comprising an amino acid sequence represented by SEQ ID NO: 3 or 5. [2] A mutated protein comprising an amino acid sequence represented by SEQ ID NO: 3 or 5, wherein 1-20 amino acids are missing, substituted, inserted, or added to the amino acid sequence. [3] A homologous protein comprising an amino acid sequence with at least 90% identity to an amino acid sequence represented by SEQ ID NO: 3 or 5.

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Inventors:

HORI KAZUMASA (JP)
UJIHARA TETSURO (JP)
ATAKA YUSUKE (JP)

Application Number:

PCT/JP2023/012607

Publication Date:

November 02, 2023

Filing Date:

March 28, 2023

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Assignee:

KYOWA HAKKO BIO CO LTD (JP)

International Classes:

C12N15/54; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12P19/30

Domestic Patent References:

WO2020129997A1

2020-06-25

Other References:

DATABASE EMBL ANONYMOUS : "Bisgaardia hudsonensis nicotinamide phosphoribosyltransferase", XP093102717, retrieved from EMBL
DATABASE EMBL ANONYMOUS : "Chitinophaga rupis nicotinamide phosphoribosyltransferase", XP093102718, retrieved from EMBL

Attorney, Agent or Firm:

HASEGAWA Yoshiki et al. (JP)

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