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Title:
PROCESS FOR CONTINUOUS MANUFACTURE OF BIOMOLECULES
Document Type and Number:
WIPO Patent Application WO/2024/068754
Kind Code:
A1
Abstract:
The invention relates to a system (1) for continuous manufacture of biomolecules comprising feed tanks (2) suitable for storing products and a reaction chamber (4) designed to be fed with products from said feed tanks which form in the reaction chamber a reaction phase, said reaction chamber being designed to manufacture said biomolecules from said reaction phase. The system of the invention comprises a scale tank (6) in fluid communication to the reaction chamber and suitable for storing an immiscible phase and a monitoring and control unit (2) set to control the injection flow rate of the immiscible phase into the reaction chamber in order to keep constant a certain filling level of the reaction chamber according to the amount of reaction phase to be injected into the reaction chamber to manufacture a certain amount of biomolecules.

Inventors:
STRUBE JOCHEN (DE)
SCHMIDT AXEL (DE)
HELGERS HERIBERT (DE)
HENGELBROCK AILINA (DE)
BONNEVILLE CHRISTOPHE (FR)
VETTER FLORIAN (DE)
JUCKERS ALEX (DE)
Application Number:
PCT/EP2023/076748
Publication Date:
April 04, 2024
Filing Date:
September 27, 2023
Export Citation:
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Assignee:
TECHNISCHE UNIV CLAUSTHAL (DE)
DILLICO (FR)
International Classes:
B01J4/00; A61K39/00; B01J19/00; B01J19/24; C12N15/10; C12P19/34; C12Q1/6844
Domestic Patent References:
WO2021212034A12021-10-21
WO2020146425A12020-07-16
WO2020002598A12020-01-02
WO2021212034A12021-10-21
Attorney, Agent or Firm:
IP TRUST (FR)
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