Title:
PREPARATION METHOD FOR TOPRAMEZONE INTERMEDIATE
Document Type and Number:
WIPO Patent Application WO/2024/088279
Kind Code:
A1
Abstract:
Disclosed in the present invention is a synthesis method for a 4-methylthio-3-aldehyde-2-methylbenzoate topramezone intermediate represented by general formula V. The reaction synthesis route thereof is as follows: R is an ester, carboxylic acid, amide or cyano group, R1 and R2 are independently selected from alkyls, preferably C1-C4 alkyls, and X is a halogen, preferably fluorine, chlorine, bromine and iodine. The preparation method provided in the present invention has good reaction selectivity in each step and high yield, and effectively solves technical problems in the synthesis of some other topramezone intermediates. The entire process route can easily achieve industrialization.
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Inventors:
LIU BINLONG (CN)
Application Number:
PCT/CN2023/126314
Publication Date:
May 02, 2024
Filing Date:
October 24, 2023
Export Citation:
Assignee:
PURPANA BEIJING TECH CO LTD (CN)
International Classes:
C07C323/57; C07C67/313; C07C67/317; C07C69/757; C07C69/76; C07C319/14; C07C319/20; C07C323/56
Foreign References:
| US6100421A | 2000-08-08 | |||
| CN112745270A | 2021-05-04 | |||
| CN110922367A | 2020-03-27 | |||
| CN110183392A | 2019-08-30 | |||
| CN103788083A | 2014-05-14 | |||
| JP2003327580A | 2003-11-19 |
Attorney, Agent or Firm:
BEIJING ZHIWENTONGDA INTELLECTUAL PROPERTY AGENCY (CN)
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