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Title:
PHARMACEUTICAL COMPOSITION FOR AMELIORATING AUTOIMMUNE-TYPE DISEASES
Document Type and Number:
WIPO Patent Application WO/2023/234312
Kind Code:
A1
Abstract:
Antibody preparations for treating autoimmune-type diseases such as autoimmune diseases, allergic diseases, and kidney diseases in which autoimmunity is involved have been proposed, but the administration route thereof has been limited to intravenous administration, which puts a burden on patients. Furthermore, novel medicines that inhibit kinases such as NIK are constantly needed for the development of effective drugs for treating autoimmune diseases, allergic diseases, and kidney diseases in which autoimmunity is involved. At least one compound selected from among yk-7 (formula (1)), yk-8-1, yk-8-3, M7, M9, M11, M12, M14, M15, M16, M18, and M19 having a xanthone skeleton can ameliorate autoimmune-type diseases and is capable of exhibiting an effect when taken orally.

Inventors:
NISHIDA SHOZO (JP)
TSUBAKI MASANOBU (JP)
TAKEDA TOMOYA (JP)
TANABE GENZOH (JP)
TAKASHIMA KATSUKI (JP)
Application Number:
PCT/JP2023/020138
Publication Date:
December 07, 2023
Filing Date:
May 30, 2023
Export Citation:
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Assignee:
UNIV KINKI (JP)
International Classes:
A61K31/352; A23L33/10; A61P1/04; A61P1/16; A61P1/18; A61P3/00; A61P3/10; A61P7/02; A61P7/06; A61P9/00; A61P11/02; A61P11/06; A61P13/12; A61P15/00; A61P15/06; A61P17/00; A61P17/04; A61P17/06; A61P17/14; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P27/02; A61P27/16; A61P29/00; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
WO2020130102A12020-06-25
WO2022138735A12022-06-30
Foreign References:
CN102432602A2012-05-02
CN102432601A2012-05-02
JP2017031146A2017-02-09
Attorney, Agent or Firm:
HIROKOH Masaki (JP)
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