PEPTIDE-LOADED ANTIGEN PRESENTING CELL-DERIVED EXTRACELLULAR BLEBS AS A MOLECULARLY TARGETED VACCINE

Title:

PEPTIDE-LOADED ANTIGEN PRESENTING CELL-DERIVED EXTRACELLULAR BLEBS AS A MOLECULARLY TARGETED VACCINE

Document Type and Number:

WIPO Patent Application WO/2024/050486

Kind Code:

A3

Abstract:

The disclosure provides for vaccine preparations compnsing isolated or purified extracellular blebs that display engineered MHC I and MHC II peptides that target specific antigen(s) or a specific epitope(s) from a pathogen, and uses thereof, including for vaccination against the pathogen and disease.

Inventors:

KWON YOUNG JIK (US)
CHUNG JEE YOUNG (US)

Application Number:

PCT/US2023/073255

Publication Date:

April 25, 2024

Filing Date:

August 31, 2023

Export Citation:

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Assignee:

UNIV CALIFORNIA (US)

International Classes:

A61K39/12; A61K39/39; C12N5/0783; A61K35/17; C07K16/08

Attorney, Agent or Firm:

BAKER, Joseph, R., Jr. (US)

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