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Title:
PARACOCCUS AMINOVORANS BM109 STRAIN AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/080441
Kind Code:
A1
Abstract:
The present invention provides: a Paracoccus aminovorans BM109 strain (accession number KCTC 15059BP), which is excellent for removing trimethylamine (TMA) or trimethylamine N-oxide (TMAO); and a pharmaceutical composition for preventing or treating diseases caused by TMA or TMAO, a health functional food composition for preventing or alleviating diseases caused by TMA or TMAO, and a feed composition for preventing or alleviating diseases caused by TMA or TMAO, all of which comprise the strain as an active ingredient.

Inventors:
KIM JUN BEOM (KR)
SEO MU KYUNG (KR)
HONG MIN YOUNG (KR)
Application Number:
PCT/KR2022/018514
Publication Date:
April 18, 2024
Filing Date:
November 22, 2022
Export Citation:
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Assignee:
BIOME INC (KR)
International Classes:
C12N1/20; A23K10/16; A23L33/135; A61K35/74; A61P3/00; A61P9/00; A61P13/12; C12R1/01
Domestic Patent References:
WO2017075485A12017-05-04
Other References:
JAKUB CZARNECKI: "Diversity of Methylotrophy Pathways in the Genus Paracoccus ( Alphaproteobacteria )", CURRENT ISSUES IN MOLECULAR BIOLOGY, CAISTER ACADEMIC, WYMONDHAM, GB, 1 January 2019 (2019-01-01), GB , pages 117 - 132, XP093158228, ISSN: 1467-3037, DOI: 10.21775/cimb.033.117
T. URAKAMI: "Paracoccus aminophilus sp. nov. and Paracoccus aminovorans sp. nov., Which Utilize N,N-Dimethylformamide", INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, vol. 40, no. 3, 1 July 1990 (1990-07-01), pages 287 - 291, XP093158229, ISSN: 0020-7713, DOI: 10.1099/00207713-40-3-287
SONG-GUN KIM: "Isolation and characterization of novel halotolerant and/or halophilic denitrifying bacteria with versatile metabolic pathways for the degradation of trimethylamine", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 225, no. 2, 2 May 2024 (2024-05-02), pages 263 - 269, XP093158231, ISSN: 0378-1097, DOI: 10.1016/S0378-1097(03)00530-5
DAVIDSON, V.L. ; KUMAR, M.A.: "Inhibition by trimethylamine of methylamine oxidation by Paracoccus denitrificans and bacterium W3A1", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGETICS., AMSTERDAM, NL, vol. 1016, no. 3, 26 April 1990 (1990-04-26), NL , pages 339 - 343, XP023349695, ISSN: 0005-2728, DOI: 10.1016/0005-2728(90)90166-2
Attorney, Agent or Firm:
INVENSYNC INTELLECTUAL PROPERTY GROUP (KR)
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