NOVEL CELLULAR IMMUNE-POTENTIATING ADJUVANT

WIPO Patent Application WO/2023/219160

A1

The present invention provides a protein having an adjuvant activity of potentiating cellular immunity. More specifically, provided is an adjuvant composition for potentiating cellular immunity, said composition containing a protein having an amino acid sequence selected from SEQ ID NOS: 1-4, or a variant thereof.

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MIZUNO SATORU (JP)
MATSUO KAZUHIRO (JP)
CHUMA YASUSHI (JP)
SHIBUYA YUKIHIRO (JP)

PCT/JP2023/017885

November 16, 2023

May 12, 2023

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JAPAN BCG LABORATORY (JP)

A61K39/39; A61K39/00; A61P35/00; A61P37/04; A61P43/00; C07K14/35; C12N1/21; C12N15/63; C12P21/02

WO2011159814A2

2011-12-22

JP2013543493A

2013-12-05

KARIYONE, AI; TAKATSU, KIYOSHI: "Adjuvant Effect of Mycobacterium tuberculosis Protein. Infectious Disease.", INFECTIOUS DISEASES, vol. 40, no. 3, 1 January 2010 (2010-01-01), pages 12, 24 - 28, XP009550271, ISSN: 0301-259X
OKAMURA, TOMOTAKA ET AL.: "Regulation of Primate AIDS Model of AIDS Viruses Incorporating Adjuvant Molecule Ag85B", PROGRAM AND ABSTRACTS OF THE 25TH ANNUAL MEETING OF THE JAPANESE SOCIETY FOR VACCINOLOGY; DECEMBER 3RD TO 5TH, 2021, JAPANESE SOCIETY FOR VACCINOLOGY, JP, 1 January 2021 (2021-01-01) - 5 December 2021 (2021-12-05), JP, pages 136, XP009550639

TANAKA Shinichiro et al. (JP)

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