Title:
NOVEL ANTI-CANCER VACCINE COMPOSITION AND VACCINATION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/090956
Kind Code:
A1
Abstract:
The present invention provides an anticancer vaccine composition and a vaccination method using same, wherein the PD-L1 or PD-L1-T epitope protein is expressed on the surface of a Lactobacillus sp. strain to induce vaccination, whereby the onset and growth of various cancers including colorectal cancer can be effectively suppressed.
Inventors:
LEE SEUNG HOON (KR)
KIM CHUL-JOONG (KR)
LEE MYUNG SHIN (KR)
LEE JONG SOO (KR)
KANG YUN HEE (KR)
HAN SEUNG RO (KR)
KIM CHUL-JOONG (KR)
LEE MYUNG SHIN (KR)
LEE JONG SOO (KR)
KANG YUN HEE (KR)
HAN SEUNG RO (KR)
Application Number:
PCT/KR2022/018361
Publication Date:
May 25, 2023
Filing Date:
November 18, 2022
Export Citation:
Assignee:
EULJI UNIV INDUSTRY ACADEMY COOPERATION FOUNDATION (KR)
IAC IN NAT UNIV CHUNGNAM (KR)
IAC IN NAT UNIV CHUNGNAM (KR)
International Classes:
C12N15/74; A61K38/00; A61K39/00; A61P35/00; C07K14/705
Foreign References:
| US20210236614A1 | 2021-08-05 | |||
| KR20210046811A | 2021-04-28 | |||
| KR20210098148A | 2021-08-10 | |||
| US9669078B2 | 2017-06-06 | |||
| KR102401860B1 | 2022-05-24 | |||
| KR102421307B1 | 2022-07-14 |
Other References:
SHAMAILA MUNIR AHMAD, EVELINA MARTINENAITE, MORTEN HANSEN, NIELS JUNKER, TROELS HOLZ BORCH, ÖZCAN MET, MARCO DONIA, INGE MARI: "PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine.", ONCOIMMUNOLGY, LANDES BIOSCIENCE, US, vol. 5, no. 8, 1 August 2016 (2016-08-01), US , pages e1202391-1 - e1202391-9, XP002773828, ISSN: 2162-4011, DOI: 10.1080/2162402X.2016.1202391
Attorney, Agent or Firm:
HAN, Yun Ho (KR)
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