Title:
NONENZYMATIC BIOSENSOR BASED ON METAL-MODIFIED POROUS BORON-DOPED DIAMOND ELECTRODE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/228016
Kind Code:
A1
Abstract:
Disclosed are a nonenzymatic biosensor based on a metal-modified porous boron-doped diamond electrode, and a preparation method therefor and the use thereof. A working electrode of the nonenzymatic biosensor is a metal-modified porous boron-doped diamond electrode comprising a silicon wafer substrate and an electrode working layer, wherein the electrode working layer is arranged on a surface of the silicon wafer substrate, the electrode working layer is a porous boron-doped diamond layer, the surface of which is modified with metal nanoparticles, and the pore surface of the porous boron-doped diamond layer contains a sp2 phase. In the present invention, by combining chemical vapor deposition and magnetron sputtering and by means of a tubular atmosphere annealing furnace and an electrochemical workstation, the preparation of a multi-metal-modified porous boron-doped diamond composite electrode is realized. The electrode has the characteristics of a high sensitivity and stability, and a high resolution, and can be widely used in the fields of the construction of electrochemical biosensors, the detection of heavy metals, etc.
Inventors:
WEI QIUPING (CN)
MA LI (CN)
ZHOU KECHAO (CN)
ZENG SICHAO (CN)
ZHU RUITONG (CN)
YANG WANLIN (CN)
MA LI (CN)
ZHOU KECHAO (CN)
ZENG SICHAO (CN)
ZHU RUITONG (CN)
YANG WANLIN (CN)
Application Number:
PCT/CN2021/092645
Publication Date:
November 18, 2021
Filing Date:
May 10, 2021
Export Citation:
Assignee:
UNIV CENTRAL SOUTH (CN)
International Classes:
G01N27/327; B82Y15/00; B82Y40/00; C23C14/16; C23C14/35; C23C14/58; C23C16/27; C23C28/00; C25D15/00; C25F5/00; G01N27/30
Foreign References:
| CN111579612A | 2020-08-25 | |||
| CN106435518A | 2017-02-22 |
Other References:
GONG ZHENZHI, NAIXIU HU, WENTAO YE, KUANGZHI ZHENG, CAN LI, LI MA, QIUPING WEI, ZHIMING YU, KECHAO ZHOU, NAN HUANG, CHENG-TE LIN, : "High-performance Non-enzymatic Glucose Sensor Based on Ni/Cu/boron-doped Diamond Electrode", JOURNAL OF ELECTROANALYTICAL CHEMISTRY, vol. 841, 21 March 2019 (2019-03-21), pages 135 - 141, XP055867408, ISSN: 1873-2569, DOI: 10.1016/j.jelechem.2019.03.043
DENG ZEJUN; LONG HANGYU; WEI QIUPING; YU ZHIMING; ZHOU BO; WANG YIJIA; ZHANG LONG; LI SHASHA; MA LI; XIE YOUNENG; MIN JIE: "High-performance non-enzymatic glucose sensor based on nickel-microcrystalline graphite-boron doped diamond complex electrode", SENSORS AND ACTUATORS B: CHEMICAL, ELSEVIER BV, NL, vol. 242, 1 January 1900 (1900-01-01), NL , pages 825 - 834, XP029881991, ISSN: 0925-4005, DOI: 10.1016/j.snb.2016.09.176
HU JING-YUAN, LI MA, CHENG-WU ZHU, RUI-QIONG MEI: "Fabrication of Porous Boron-doped Diamond Membrane Electrode by Nickel Catalysis and Its Electrochemical Oxidation Degradation of Dye Wastewater", KUANGYE-GONGCHENG = MINING AND METALLURGICAL ENGINEERING, vol. 38, no. 6, 31 December 2018 (2018-12-31), XP055867415, ISSN: 0253-6099, DOI: 10.3969/j.issn.0253-6099.2018.06.034
DENG ZEJUN; LONG HANGYU; WEI QIUPING; YU ZHIMING; ZHOU BO; WANG YIJIA; ZHANG LONG; LI SHASHA; MA LI; XIE YOUNENG; MIN JIE: "High-performance non-enzymatic glucose sensor based on nickel-microcrystalline graphite-boron doped diamond complex electrode", SENSORS AND ACTUATORS B: CHEMICAL, ELSEVIER BV, NL, vol. 242, 1 January 1900 (1900-01-01), NL , pages 825 - 834, XP029881991, ISSN: 0925-4005, DOI: 10.1016/j.snb.2016.09.176
HU JING-YUAN, LI MA, CHENG-WU ZHU, RUI-QIONG MEI: "Fabrication of Porous Boron-doped Diamond Membrane Electrode by Nickel Catalysis and Its Electrochemical Oxidation Degradation of Dye Wastewater", KUANGYE-GONGCHENG = MINING AND METALLURGICAL ENGINEERING, vol. 38, no. 6, 31 December 2018 (2018-12-31), XP055867415, ISSN: 0253-6099, DOI: 10.3969/j.issn.0253-6099.2018.06.034
Attorney, Agent or Firm:
CHANGSHA RONG ZHI PATENT AGENCY (CN)
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