Title:
MULTI-CHAMBER DEVICE FOR DETECTING PATHOGENS/MOLECULES AND METHODS OF USING SAME
Document Type and Number:
WIPO Patent Application WO/2024/059037
Kind Code:
A3
Abstract:
A method of positively detecting a target pathogen/molecule within a fluid sample and related test devices are described. The device includes a plurality of chambers in adjacent, spaced-apart relationship, and a plurality of isolation valves selectively actuatable to control fluid flow into and out of one or more of the plurality of chambers. The method includes providing the fluid sample into a first chamber of the device; opening a first one of the isolation valves to allow the fluid sample to flow from the first chamber into a second chamber, the second chamber containing an amplification reagent; opening a second one of the isolation valves to allow the fluid sample to flow from the second chamber into a third chamber, the third chamber containing a CRISPR/Cas reagent; illuminating the fluid sample in third chamber with light; and determining whether the fluid sample in the third chamber fluoresces in response to the light.
Inventors:
DOLLERY STEPHEN J (US)
DU KE (US)
BAO MENGDI (US)
ZHANG SHUHUAN (US)
LIU RUI (US)
WIGGINS TARALYN J (US)
TOBIN GREGORY J (US)
DU KE (US)
BAO MENGDI (US)
ZHANG SHUHUAN (US)
LIU RUI (US)
WIGGINS TARALYN J (US)
TOBIN GREGORY J (US)
Application Number:
PCT/US2023/032485
Publication Date:
April 25, 2024
Filing Date:
September 12, 2023
Export Citation:
Assignee:
BIOLOGICAL MIMETICS INC (US)
International Classes:
C12Q1/04; C12Q1/02; C12Q1/6888; C12Q1/18
Attorney, Agent or Firm:
BODDIE, II, Needham, J. (US)
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