Title:
MODIFIED AAV VECTORS FOR GENE THERAPY
Document Type and Number:
WIPO Patent Application WO/2024/044691
Kind Code:
A3
Abstract:
Disclosed herein are compositions comprising chemically modified adeno-associated viruses (AAV) engineered by chemical modification of capsid proteins, whether wildtype or engineered, and methods of using such modified AAVs for therapeutic use wherein the modified AAVs are re-directed to specific organs/tissues relative to the unmodified AAV.
Inventors:
XIAO WEIDONG (US)
LAM ANH KIM (US)
LAM ANH KIM (US)
Application Number:
PCT/US2023/072826
Publication Date:
April 25, 2024
Filing Date:
August 24, 2023
Export Citation:
Assignee:
UNIV INDIANA TRUSTEES (US)
International Classes:
C12Q1/70; C07K14/075; C12N15/09; C12N15/86; G01N33/68; H01J49/26
Attorney, Agent or Firm:
PILCHER, Jessamine G. et al. (US)
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