Title:
MICROFLUIDIC CHIP AND METHOD FOR USING SAME, MICROFLUIDIC SYSTEM AND METHOD FOR MANUFACTURING CONDUCTIVE COVER BOARD
Document Type and Number:
WIPO Patent Application WO/2024/078548
Kind Code:
A1
Abstract:
A microfluidic chip (304) and a method for using the same, a microfluidic system, and a method for manufacturing a conductive cover board (4). The chip (304) comprises an extraction assembly (1) and an amplification assembly (2), wherein the extraction assembly (1) comprises a lysis chamber (100), a first valve chamber (101), a cleaning chamber (102, 103) and a second valve chamber (104) that are connected in sequence; the amplification assembly (2) comprises a chip substrate (6), a barrier layer (5) and a conductive cover board (4); the barrier layer (5) is located between the chip substrate (6) and the conductive cover board (4), and the barrier layer (5), the chip substrate (6) and the conductive cover board (4) enclose an elution chamber (21), a liquid path chamber (22), and an amplification chamber (23) that are connected in sequence, and the elution chamber (21) is in communication with the second valve chamber (104) via a first passage (24); an electrode array (7) is provided on the chip substrate (6); the conductive cover board (4) is provided with a bottom-opening cavity (400) on a side adjacent to the chip substrate (6), and the elution chamber (21) comprises the cavity (400); the electrode array (7) is located directly below the elution chamber (21), the liquid path chamber (22), and the amplification chamber (23); the amplification assembly (2) further comprises a storage chamber (20) for storing surfactant, and the storage chamber (20) is in communication with the elution chamber (21) via a second passage (25); and the liquid path chamber (22) comprises a liquid storage cavity (220), and the liquid storage chamber (220) is adjacent to the elution chamber (21); and the thickness of the chamber (400) is in a range from 0.6 mm to 2 mm in the thickness direction of the microfluidic chip (304).
Inventors:
CHEN TIANLAN (CN)
LIU CHENGHAI (CN)
WU ZHENG (CN)
WU XIANGJUN (CN)
LIANG MEIXIAN (CN)
CHENG KEXUAN (CN)
LIU CHENGHAI (CN)
WU ZHENG (CN)
WU XIANGJUN (CN)
LIANG MEIXIAN (CN)
CHENG KEXUAN (CN)
Application Number:
PCT/CN2023/124095
Publication Date:
April 18, 2024
Filing Date:
October 11, 2023
Export Citation:
Assignee:
DIGIFLUIDIC BIOTECH LTD (CN)
International Classes:
B01L3/00
Domestic Patent References:
| WO2022187381A1 | 2022-09-09 |
Foreign References:
| CN218393734U | 2023-01-31 | |||
| CN111704994A | 2020-09-25 | |||
| CN114534805A | 2022-05-27 | |||
| CN210752735U | 2020-06-16 | |||
| CN113083389A | 2021-07-09 | |||
| CN110452802A | 2019-11-15 | |||
| US20190176153A1 | 2019-06-13 | |||
| US20130288254A1 | 2013-10-31 |
Attorney, Agent or Firm:
INNOPAT INTELLECTUAL PROPERTY CO., LTD. (CN)
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