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Title:
MICROBIAL FERMENTATION CONTROL METHOD, APPARATUS AND SYSTEM, DEVICE, AND MEDIUM
Document Type and Number:
WIPO Patent Application WO/2024/061127
Kind Code:
A1
Abstract:
The present invention relates to the field of microbial fermentation control, and particularly provides a microbial fermentation control method, apparatus and system, a device, and a medium. The microbial fermentation control method comprises: collecting tail gas monitoring data in a microbial fermentation process; inputting the tail gas monitoring data into a quantitative relation model for data analysis, and outputting a substrate consumption rate by the quantitative relation model; determining, according to the substrate consumption rate, a feeding speed instruction, the feeding speed instruction being used for indicating feeding in the fermentation process according to a feeding speed.

Inventors:
ZHAO CHANGCHUN (CN)
ZHOU YAOYAO (CN)
WANG DONGSHENG (CN)
LI TENG (CN)
ZHANG HAOQIAN (CN)
Application Number:
PCT/CN2023/119119
Publication Date:
March 28, 2024
Filing Date:
September 15, 2023
Export Citation:
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Assignee:
BEIJING BLUEPHA MICROBIOLOGY TECH CO LTD (CN)
International Classes:
C12Q3/00; C12M1/34; C12M1/36; C12P7/625
Domestic Patent References:
WO2017049751A12017-03-30
Foreign References:
CN115948622A2023-04-11
CN113403193A2021-09-17
CN102353798A2012-02-15
US20180245113A12018-08-30
US20150010899A12015-01-08
Other References:
KARASAVVAS EVGENIOS, CHATZIDOUKAS CHRISTOS: "Model-based dynamic optimization of the fermentative production of polyhydroxyalkanoates (PHAs) in fed-batch and sequence of continuously operating bioreactors", BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER, AMSTERDAM, NL, vol. 162, 1 October 2020 (2020-10-01), NL , pages 107702, XP093150227, ISSN: 1369-703X, DOI: 10.1016/j.bej.2020.107702
YAN JING-HUI, SONG SHUI-SHAN, JIA ZHEN-HUA, WU MENG, ZHANG XIAO-BING: "Studies on the production of PHA by fed-batch culture with DO-control method employing Escherchia coli XL1-Blue(pKSABC)", CHINESE MASTER’S THESES FULL-TEXT DATABASE, AGRICULTURAL SCIENCE AND TECHNOLOGY, vol. 22, no. 3, 30 September 2005 (2005-09-30), pages 55 - 58, XP009553386, ISSN: 1001-9383, DOI: 10.16191/j.cnki.hbkx.2005.03.017
Attorney, Agent or Firm:
CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)
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