METHOD FOR PRODUCING HYDROGEL MICROCAPSULES, KIT FOR PRODUCING CAPSULES, AND USE THEREFOR

Title:

METHOD FOR PRODUCING HYDROGEL MICROCAPSULES, KIT FOR PRODUCING CAPSULES, AND USE THEREFOR

Document Type and Number:

WIPO Patent Application WO/2020/184680

Kind Code:

A1

Abstract:

This method for producing capsules includes a step in which a suspension obtained by suspending, in an oil (10), a sol (9) of a thermoresponsive polymer including a core 8 formed from a gel of ionically-bonded polymer, is cooled to gel the thermoresponsive polymer and form a hydrogel shell (17), whereafter the core is transformed into a sol using a chelating agent to hollow out the interior.

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Inventors:

AOKI HIROYOSHI (JP)
YAMAGATA YUTAKA (JP)
OHKUMA MORIYA (JP)
YUKI MASAHIRO (JP)

Application Number:

PCT/JP2020/010927

Publication Date:

September 17, 2020

Filing Date:

March 12, 2020

Export Citation:

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Assignee:

RIKEN (JP)

International Classes:

C08L101/00; A61K9/50; A61K47/14; A61K47/32; A61K47/36; A61K47/38; A61K47/42; B01J13/08

Foreign References:

JP2009537268A	2009-10-29
JP2008515434A	2008-05-15
CN104887643A	2015-09-09

Other References:

REIS, C. P. ET AL.: "Review and current status of emulsion/dispersion technology using an internal gelation process for the design of alginate particles", JOURNAL OF MICROENCAPSULATION, vol. 23, no. 3, 2006, pages 245 - 257, XP002631972, DOI: 10.1080/02652040500286086

Attorney, Agent or Firm:

HARAKENZO WORLD PATENT & TRADEMARK (JP)

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