Title:
METHOD FOR PRODUCING γ-GLUTAMYLCYSTEINE AND GLUTATHIONE
Document Type and Number:
WIPO Patent Application WO/2016/017631
Kind Code:
A1
Abstract:
The problem to be solved by the present invention is to provide a method for producing glutathione and γ-glutamylcysteine, which is a precursor of glutathione, at high yield. This method for producing glutathione includes, as a means for solving the above problem, a step A' for producing γ-glutamylcysteine by reacting L-cysteine and L-glutamic acid in a low-oxygen atmosphere, and a step B' for producing glutathione by reacting γ-glutamylcysteine and glycine in a low-oxygen atmosphere.
Inventors:
NOJIRI MASUTOSHI (JP)
YASOHARA YOSHIHIKO (JP)
YASOHARA YOSHIHIKO (JP)
Application Number:
PCT/JP2015/071358
Publication Date:
February 04, 2016
Filing Date:
July 28, 2015
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
C12P11/00; C12N15/09; C12P13/00; C12P21/02; C12N9/00
Foreign References:
| JPS5577888A | 1980-06-12 | |||
| JP2012085637A | 2012-05-10 | |||
| JPS60196197A | 1985-10-04 |
Other References:
JANOWIAK, B. E. ET AL.: "Glutathione Synthesis in Streptococcus agalactiae ONE PROTEIN ACCOUNTS FOR y- GLUTAMYLCYSTEINE SYNTHETASE AND GLUTATHIONE SYNTHETASE ACTIVITIES", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, no. 12, 2005, pages 11829 - 11839, XP055249654, ISSN: 1083-351X, DOI: doi:10.1074/jbc.M414326200
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
Yusuke Hiraki (JP)
Download PDF:
Previous Patent: PLANT DESIGN ASSIST DEVICE AND PLANT DESIGN ASSIST PROGRAM
Next Patent: ELECTROACOUSTIC CONVERSION FILM AND ELECTROACOUSTIC CONVERTER
Next Patent: ELECTROACOUSTIC CONVERSION FILM AND ELECTROACOUSTIC CONVERTER