Title:
METHOD FOR PRODUCING CARRIER FOR CHROMATOGRAPHIC USE, METHOD FOR PRODUCING CHROMATOGRAPHY COLUMN, AND CARRIER FOR CHROMATOGRAPHIC USE
Document Type and Number:
WIPO Patent Application WO/2022/202467
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a carrier for chromatographic use which has excellent liquid permeability and also has excellent pressure resistance properties when a liquid is passed through the carrier. Provided is a method for producing a carrier for chromatographic use, the method comprising the steps 1 and 2 mentioned below, in which a solid support prepared in step 1 comprises porous particles to each of which no ligand is fixed or porous particles to each of which a ligand is fixed. (Step 1) A step for preparing the solid support. (Step 2) A step for subjecting the solid support to sieve classification to adjust the solid support in such a manner that the coefficient of variation in volume-based particle diameter distribution of the porous particles when a ligand is fixed can become 1% to 22% inclusive and a value [d1/d50] determined by dividing a volume-based cumulative 1% particle diameter by a volume-based cumulative 50% particle diameter d50 can become 0.55 to 1.0 inclusive.
Inventors:
KOBAYASHI KUNIHIKO (JP)
AKIYAMA MINATO (JP)
INOUE YUKIYA (JP)
KIKUCHI MASAHIRO (JP)
AKIYAMA MINATO (JP)
INOUE YUKIYA (JP)
KIKUCHI MASAHIRO (JP)
Application Number:
PCT/JP2022/011495
Publication Date:
September 29, 2022
Filing Date:
March 15, 2022
Export Citation:
Assignee:
JSR CORP (JP)
International Classes:
B01D15/38; B01J20/281; B01J20/285
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Other References:
LJUNGQUIST C ET AL., EUR. J. BIOCHEM., vol. 186, 1989, pages 557 - 561
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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