Title:
METHOD FOR PREPARING RUTHENIUM CARBENE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2022/052307
Kind Code:
A1
Abstract:
The present invention relates to the technical field of catalyst synthesis, and provides a method for preparing a ruthenium carbene compound. The method comprises the following steps: (1) dissolving a ruthenium metal salt RuX3nH2O in a solvent, and performing complex reaction with a ligand L1 under the condition of a reducing agent; (2) directly adding, without separation, a product obtained from step (1) into alkyne as shown in formula I to perform reaction; and (3) directly adding, without separation, a product obtained from step (2) into an olefin as shown in formula II to perform reaction, thereby obtaining a ruthenium carbene compound as shown in formula III. Gaseous explosive ethylene or acetylene gas is prevented from being applied or generated in a process route; a reaction condition is mild, an extremely low temperature or a high temperature is not required; and an operation is simple. Compared with existing routes, the process has stronger operability and economic advantages.
Inventors:
XU ZHIMING (CN)
YOU YINGFENG (CN)
HUANG JINKUN (CN)
XIE DEJIAN (CN)
HU FEI (CN)
YOU YINGFENG (CN)
HUANG JINKUN (CN)
XIE DEJIAN (CN)
HU FEI (CN)
Application Number:
PCT/CN2020/130200
Publication Date:
March 17, 2022
Filing Date:
November 19, 2020
Export Citation:
Assignee:
XILING LAB CO LTD (CN)
International Classes:
C07F15/00; B01J31/22; B01J31/24
Foreign References:
| CN101990543A | 2011-03-23 | |||
| CN107233925A | 2017-10-10 |
Other References:
XIA LIANG ET AL.: "ONE-POT SYNTHESIS OF 2nd RUTHENIUM GRUBBS CATALYST FOR PREPARATION OF ONE STAPLED PEPTIDE", CHEMISTRY OF NATURAL COMPOUNDS, vol. 55, no. 3, 31 May 2019 (2019-05-31), pages 525 - 527, XP036817892, DOI: 10.1007/s10600-019-02730-7
Attorney, Agent or Firm:
GAOYUNG INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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