Title:
METHOD FOR PREPARING HIGH-CONTENT GANODERMA TRITERPENE EXTRACT
Document Type and Number:
WIPO Patent Application WO/2024/001714
Kind Code:
A1
Abstract:
Disclosed is a method for preparing a high-content Ganoderma triterpene extract, comprising the following steps of: carrying out ultrasonic extraction on a dry Ganoderma powder with water 2-3 times, with 30-90 minutes each time, filtering, combining obtained filtrates, drying to obtain a Ganoderma aqueous extract solid, adding ethanol to the Ganoderma aqueous extract solid, carrying out ultrasonic extraction for 30-90 minutes, filtering, and drying an obtained filtrate at a low temperature to obtain the high-content Ganoderma triterpene extract. The present invention can save a large amount of ethanol, the extraction efficiency is high, and the obtained solid has a high content of Ganoderma triterpene.
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Inventors:
FENG PENG (CN)
ZHOU YAJIE (CN)
CHEN XIAOHONG (CN)
SHEN JIAN (CN)
QIAN YIFAN (CN)
ZHOU YAJIE (CN)
CHEN XIAOHONG (CN)
SHEN JIAN (CN)
QIAN YIFAN (CN)
Application Number:
PCT/CN2023/099176
Publication Date:
January 04, 2024
Filing Date:
June 08, 2023
Export Citation:
Assignee:
NANJING ZHONGKE PHARMACEUTICAL CO LTD (CN)
ZHONGKE HEALTH IND GROUP CORP LTD (CN)
ZHONGKE HEALTH IND GROUP CORP LTD (CN)
International Classes:
A61K36/074; B01D11/02
Foreign References:
| CN115040553A | 2022-09-13 | |||
| CN111346118A | 2020-06-30 | |||
| CN109893548A | 2019-06-18 | |||
| CN110330575A | 2019-10-15 |
Other References:
UILING XU ，, GUO SIYANG, WANG YAWEN, YANG JINGLIN, FU LIXIN, DING CAIHANG, FU CHUNMEI: "Optimization of the subcritical water extraction technology of ganoderic acids from the fruiting body of Ganoderma lucidum", WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 34, no. 4, 16 July 2019 (2019-07-16), pages 393 - 395, XP093125144
SONG-JUN YAO, HUANG SHENG-QUAN, CHEN ZHUANG-YAO, ZENG QING-XIAO: "Ultrasonic-assisted Extraction of the Triterpenoids from Ganoderma lucidum", MODERN FOOD SCIENCE AND TECHNOLOGY, vol. 25, no. 10, 15 October 2009 (2009-10-15), pages 1220 - 1223, XP093125146, DOI: 10.13982/j.mfst.1673-9078.2009.10.034
QIONG-FANG HU, DONG JIAN-SHENG; GAO WEN-GENG: "Extraction and Determination of Triterpene Compounds in Ganoderma lucidum Fermented Powder", FOOD RESEARCH AND DEVELOPMENT, TIANJIN SHI SHIPIN YANJIUSUO, CN, vol. 39, no. 10, 20 May 2018 (2018-05-20), CN , pages 104 - 109, XP093125152, ISSN: 1005-6521, DOI: 10.3969/j.issn.1005-6521.2018.10.019
YUAN YUAN, YANG YI, KAI GUI-QING , PAN JIAN: "Study on the Extractive Technique of Triterpenoids from Ganoderma lucidum", ANHUI CHEMICAL INDUSTRY, vol. 33, no. 4, 15 August 2007 (2007-08-15), pages 27 - 29, XP093125158
SONG-JUN YAO, HUANG SHENG-QUAN, CHEN ZHUANG-YAO, ZENG QING-XIAO: "Ultrasonic-assisted Extraction of the Triterpenoids from Ganoderma lucidum", MODERN FOOD SCIENCE AND TECHNOLOGY, vol. 25, no. 10, 15 October 2009 (2009-10-15), pages 1220 - 1223, XP093125146, DOI: 10.13982/j.mfst.1673-9078.2009.10.034
QIONG-FANG HU, DONG JIAN-SHENG; GAO WEN-GENG: "Extraction and Determination of Triterpene Compounds in Ganoderma lucidum Fermented Powder", FOOD RESEARCH AND DEVELOPMENT, TIANJIN SHI SHIPIN YANJIUSUO, CN, vol. 39, no. 10, 20 May 2018 (2018-05-20), CN , pages 104 - 109, XP093125152, ISSN: 1005-6521, DOI: 10.3969/j.issn.1005-6521.2018.10.019
YUAN YUAN, YANG YI, KAI GUI-QING , PAN JIAN: "Study on the Extractive Technique of Triterpenoids from Ganoderma lucidum", ANHUI CHEMICAL INDUSTRY, vol. 33, no. 4, 15 August 2007 (2007-08-15), pages 27 - 29, XP093125158
Attorney, Agent or Firm:
BEIJING SICHUANG DACHENG INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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