Title:
METHOD FOR EXTRACTING MICROVESICLES FROM BIOLOGICAL SAMPLE
Document Type and Number:
WIPO Patent Application WO/2020/166978
Kind Code:
A9
Abstract:
The present invention relates to a method for extracting microvesicles from a biological sample, the method comprising the steps of: adding a polyvalent cationic material to the biological sample to form an aggregate in which the microvesicles and the polyvalent cationic material are aggregated by electrical force; capturing the aggregate by a capture filter while the biological sample including the aggregate passes through the capture filter; and extracting the microvesicles by allowing an elution solution to pass through the capture filter with the aggregate captured therein to isolate the microvesicles from the aggregate. Accordingly, microvesicles can be extracted using a polyvalent cationic material, without a centrifugation process.
Inventors:
SHIN SEHYUN (KR)
LEE HO YOON (KR)
NA WON-HWI (KR)
KIM JIN-HYUN (KR)
LEE HO YOON (KR)
NA WON-HWI (KR)
KIM JIN-HYUN (KR)
Application Number:
PCT/KR2020/001987
Publication Date:
May 27, 2021
Filing Date:
February 12, 2020
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
B01L3/00; B01D21/01; B01D37/03
Attorney, Agent or Firm:
JUNG, Eun Youl et al. (KR)
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