Title:
METHOD FOR BREAKING POISSON DISTRIBUTION TO FORM REACTION COMPARTMENT GROUP
Document Type and Number:
WIPO Patent Application WO/2023/093887
Kind Code:
A1
Abstract:
Provided is a method for breaking a Poisson distribution rule to form a reaction compartment group. The method comprises: preparing a to-be-detected object group, which consists of more than two to-be-detected objects; preparing a targeted reaction compound group, which consists of more than two targeted reaction compounds. The targeted reaction compounds comprise carriers, target ligands which are connected to the carriers and correspond to the to-be-detected objects and reaction reagents which are connected to the carriers and correspond to the to-be-detected objects, and optionally comprise tag molecules which are connected to the carriers and correspond to the to-be-detected objects.
Inventors:
ZHANG JINGWEI (CN)
JING XIANGYI (CN)
LIANG XUE (CN)
JING XIANGYI (CN)
LIANG XUE (CN)
Application Number:
PCT/CN2022/134738
Publication Date:
June 01, 2023
Filing Date:
November 28, 2022
Export Citation:
Assignee:
UNIV FUDAN (CN)
International Classes:
B01J19/00; C12Q1/6869; C12N15/11
Domestic Patent References:
| WO2020134612A1 | 2020-07-02 |
Foreign References:
| CN109920482A | 2019-06-21 | |||
| CN113234718A | 2021-08-10 | |||
| CN107012067A | 2017-08-04 | |||
| CN108367291A | 2018-08-03 | |||
| CN111254046A | 2020-06-09 |
Other References:
COLLINS, D. J. ET AL.: "The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation", LAB ON A CHIP, vol. 15, 30 July 2015 (2015-07-30), pages 3439 - 3459, XP055426432, DOI: 10.1039/C5LC00614G
WEN NA, ZHAO ZHAN, FAN BEIYUAN, CHEN DEYONG, MEN DONG, WANG JUNBO, CHEN JIAN: "Development of Droplet Microfluidics Enabling High-Throughput Single-Cell Analysis", MOLECULES, vol. 21, no. 7, pages 881, XP093068112, DOI: 10.3390/molecules21070881
WEN NA, ZHAO ZHAN, FAN BEIYUAN, CHEN DEYONG, MEN DONG, WANG JUNBO, CHEN JIAN: "Development of Droplet Microfluidics Enabling High-Throughput Single-Cell Analysis", MOLECULES, vol. 21, no. 7, pages 881, XP093068112, DOI: 10.3390/molecules21070881
Attorney, Agent or Firm:
BEIJING TANGSONG IP FIRM (CN)
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