Title:
KIT AND METHOD FOR DETERMINING PRESENCE OR ABSENCE OF AFFECTION OF DEMENTIA
Document Type and Number:
WIPO Patent Application WO/2024/085246
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a biomarker which can determine the presence or absence of the affection of dementia with high sensitivity and specificity by means of a simple operation; and a method, a kit, and a device which are for the determination. Provided is a method for determining the presence or absence of the affection or onset risk of dementia in a subject, the method comprising a step for calculating the ratio of the expression level of connexin 43 genes and/or the expression level of prolyl hydroxylase domain protein 3 genes and the expression level of connexin 37 genes.
Inventors:
TAGUCHI AKIHIKO (JP)
OKINAKA YUKA (JP)
SAINO ORIE (JP)
TOMONO JUN (JP)
SHINAGAWA YOSHIYUKI (JP)
OKINAKA YUKA (JP)
SAINO ORIE (JP)
TOMONO JUN (JP)
SHINAGAWA YOSHIYUKI (JP)
Application Number:
PCT/JP2023/038014
Publication Date:
April 25, 2024
Filing Date:
October 20, 2023
Export Citation:
Assignee:
KANEKA CORP (JP)
FOUNDATION FOR BIOMEDICAL RES AND INNOVATION AT KOBE (JP)
FOUNDATION FOR BIOMEDICAL RES AND INNOVATION AT KOBE (JP)
International Classes:
C12N15/09; C12M1/34; C12N15/12; C12Q1/68; C12Q1/686; C12Q1/6876
Domestic Patent References:
| WO2021177447A1 | 2021-09-10 | |||
| WO2021177448A1 | 2021-09-10 |
Foreign References:
| US20180071363A1 | 2018-03-15 |
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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