Title:
KERATIN YK93-4, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/074105
Kind Code:
A1
Abstract:
The present invention belongs to the field of biopharmaceuticals. Provided in the present invention are keratin YK93-4, a nucleic acid molecule encoding same, an expression vector containing the nucleic acid molecule, a host cell containing the expression vector or a host cell having the nucleic acid molecule integrated into the genome, as well as a method for preparing keratin YK93-4 and a pharmaceutical composition of keratin YK93-4. Further provided is the use of the above-described keratin YK93-4 and related products thereof in the preparation of drugs for treating lung cancer, lymphoma, breast cancer, melanoma, uterus myoma, hyperplasia of prostate, etc.
Inventors:
YU SHISHAN (CN)
CHEN XIAOGUANG (CN)
LIU YUNBAO (CN)
JIN JING (CN)
LI MI (CN)
QU JING (CN)
HAO MENGYAO (CN)
WANG XIAOJING (CN)
LI YONG (CN)
WANG MINGJIN (CN)
SHI GUORU (CN)
MA SHUANGGANG (CN)
JIANG HUIMIN (CN)
FU JIANG (CN)
LI SHUYING (CN)
CHEN XIAOGUANG (CN)
LIU YUNBAO (CN)
JIN JING (CN)
LI MI (CN)
QU JING (CN)
HAO MENGYAO (CN)
WANG XIAOJING (CN)
LI YONG (CN)
WANG MINGJIN (CN)
SHI GUORU (CN)
MA SHUANGGANG (CN)
JIANG HUIMIN (CN)
FU JIANG (CN)
LI SHUYING (CN)
Application Number:
PCT/CN2023/121583
Publication Date:
April 11, 2024
Filing Date:
September 26, 2023
Export Citation:
Assignee:
INST MATERIA MEDICA CAMS (CN)
International Classes:
C07K14/47; A61K38/17; A61P13/08; A61P15/14; A61P35/00; C12N1/21; C12N15/12; C12N15/70; C12P21/02
Foreign References:
| CN112724233A | 2021-04-30 | |||
| CN116535486A | 2023-08-04 |
Other References:
DATABASE Protein 28 October 2020 (2020-10-28), ANONYMOUS: "keratin, type II cuticular Hb6 [Manis pentadactyla]", XP093155359, retrieved from NCBI Database accession no. XP_036771053.1
DATABASE Protein 13 July 2022 (2022-07-13), ANONYMOUS: "Keratin, Type Ii Cuticular Hb6 [Manis pentadactyla] ", XP093155362, retrieved from NCBI Database accession no. KAI5164986.1
MU YUN-ZHU: "Mutation Analysis of the KRT86 Gene in a Child with Monilethrix ", THE CHINESE JOURNAL OF DERMATOVENEREOLOGY, vol. 30, no. 12, 18 October 2016 (2016-10-18), pages 1211 - 1213, XP093155357
DATABASE Protein 13 July 2022 (2022-07-13), ANONYMOUS: "Keratin, Type Ii Cuticular Hb6 [Manis pentadactyla] ", XP093155362, retrieved from NCBI Database accession no. KAI5164986.1
MU YUN-ZHU: "Mutation Analysis of the KRT86 Gene in a Child with Monilethrix ", THE CHINESE JOURNAL OF DERMATOVENEREOLOGY, vol. 30, no. 12, 18 October 2016 (2016-10-18), pages 1211 - 1213, XP093155357
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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