Title:
INTESTINAL TYPING DETECTION SYSTEM
Document Type and Number:
WIPO Patent Application WO/2024/082648
Kind Code:
A1
Abstract:
An intestinal typing detection system for predicting the curative effect of an immune preparation combined with platinum-containing dual-drug chemotherapy. By means of detecting the intestinal flora of a patient and analyzing abundance, the curative effect of an immune preparation combined with platinum-containing dual-drug chemotherapy on the patient is predicted, accurate classification of NSCLC patients is achieved, treatment opinions are provided, and finally accurate treatment of advanced and local advanced NSCLC patients is achieved. Accordingly, pain in patients during detection analysis and treatment is relieved, treatment costs are reduced, and the risk of complications is reduced.
Inventors:
WANG YUXUAN (CN)
LIU ZHIDONG (CN)
ZHU BAOLI (CN)
GUO YAQIONG (CN)
LI ZHENG (CN)
RUAN HONGYUN (CN)
SU CHONGYU (CN)
LI GEGE (CN)
SHI KANG (CN)
BAI ZHEXIN (CN)
WANG BING (CN)
LIU ZHIDONG (CN)
ZHU BAOLI (CN)
GUO YAQIONG (CN)
LI ZHENG (CN)
RUAN HONGYUN (CN)
SU CHONGYU (CN)
LI GEGE (CN)
SHI KANG (CN)
BAI ZHEXIN (CN)
WANG BING (CN)
Application Number:
PCT/CN2023/098704
Publication Date:
April 25, 2024
Filing Date:
June 06, 2023
Export Citation:
Assignee:
BEIJING CHEST HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV (CN)
BEIJING TUBERCULOSIS CHEST CANCER INST (CN)
BEIJING TUBERCULOSIS CHEST CANCER INST (CN)
International Classes:
C12Q1/689; C12R1/01
Domestic Patent References:
| WO2022157207A1 | 2022-07-28 |
Foreign References:
| CN115572772A | 2023-01-06 | |||
| CN111534585A | 2020-08-14 | |||
| CN115181808A | 2022-10-14 |
Other References:
石然等 (SHI, RAN ET AL.): "肠道微生态与非小细胞肺癌发生机制及治疗的研究进展 (Research Progress in Microbita and Mechanism and Treatment of Non-Small Cell Lung Cancer)", 医学综述 (MEDICAL RECAPITULATE), vol. 26, no. 18, 30 September 2020 (2020-09-30), pages 3626 - 3637
王俊等 (WANG, JUN ET AL.): "晚期非小细胞肺癌的免疫治疗进展 (Progression of Immunotherapy in Advanced Non-small Cell Lung Cancer)", 医药导报 (HERALD OF MEDICINE), vol. 37, no. 5, 31 May 2018 (2018-05-31), pages 542 - 546
SONG, PENG ET AL.: "Relationship between intestinal flora structure and metabolite analysis and immunotherapy efficacy in Chinese NSCLC patients", THORACIC CANCER, vol. 11, 31 December 2020 (2020-12-31), pages 1621 - 1632, XP055912534
王俊等 (WANG, JUN ET AL.): "晚期非小细胞肺癌的免疫治疗进展 (Progression of Immunotherapy in Advanced Non-small Cell Lung Cancer)", 医药导报 (HERALD OF MEDICINE), vol. 37, no. 5, 31 May 2018 (2018-05-31), pages 542 - 546
SONG, PENG ET AL.: "Relationship between intestinal flora structure and metabolite analysis and immunotherapy efficacy in Chinese NSCLC patients", THORACIC CANCER, vol. 11, 31 December 2020 (2020-12-31), pages 1621 - 1632, XP055912534
Attorney, Agent or Firm:
BEIJING XIANGHE INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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