Title:
INTERVERTEBRAL DISC THERAPEUTIC AGENT
Document Type and Number:
WIPO Patent Application WO/2024/063020
Kind Code:
A1
Abstract:
Provided is an intervertebral disc therapeutic agent having favorable post-transplant engraftment. This intervertebral disc therapeutic agent contains scaffold-free artificial tissue in which synovium-derived mesenchymal stem cells form a three-dimensional structure.
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Inventors:
SAKAUE MORITO (JP)
MATSUMOTO MASAYA (JP)
NAGAYA MASAHIRO (JP)
KAITO TAKASHI (JP)
KODAMA JO (JP)
HIRAI HIROMASA (JP)
MATSUMOTO MASAYA (JP)
NAGAYA MASAHIRO (JP)
KAITO TAKASHI (JP)
KODAMA JO (JP)
HIRAI HIROMASA (JP)
Application Number:
PCT/JP2023/033663
Publication Date:
March 28, 2024
Filing Date:
September 15, 2023
Export Citation:
Assignee:
TWO CELLS CO LTD (JP)
UNIV OSAKA (JP)
UNIV OSAKA (JP)
International Classes:
A61K35/32; A61P19/08; A61P43/00; C12N5/0775
Other References:
海渡貴司ほか, 間葉系幹細胞から作成した三次元複合体組織による椎間板再生, 日本整形外科学会雑誌, 2021, vol. 95, no. 8, p. S1607 (2-4-S14-3)
海渡貴司ほか, 間葉系幹細胞由来三次元複合体移植による椎間板再生, 日本整形外科学会雑誌, 15 September 2022, vol. 96, no. 8, p. S1611 (1-8-S11-2)
YOSHIKAWA HIDEKI, NORIMASA NAKAMURA, KOICHIRO TSUJI : "Non-clinical studies contributing to the application for regulatory approval of threedimensional artificial tissue derived from allogeneic synovial mesenchymal stem cells manufactured using a serum-free culture method", HEALTH, LABOR AND WELFARE SCIENTIFIC RESEARCH RESULTS DATABASE, 9 July 2018 (2018-07-09), XP093150951, Retrieved from the Internet [retrieved on 20240412]
海渡貴司ほか, 間葉系幹細胞由来三次元複合体移植による椎間板再生, 日本整形外科学会雑誌, 15 September 2022, vol. 96, no. 8, p. S1611 (1-8-S11-2)
YOSHIKAWA HIDEKI, NORIMASA NAKAMURA, KOICHIRO TSUJI : "Non-clinical studies contributing to the application for regulatory approval of threedimensional artificial tissue derived from allogeneic synovial mesenchymal stem cells manufactured using a serum-free culture method", HEALTH, LABOR AND WELFARE SCIENTIFIC RESEARCH RESULTS DATABASE, 9 July 2018 (2018-07-09), XP093150951, Retrieved from the Internet
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
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