Title:
INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2021/230293
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: an inorganic porous substrate which can be served as a precursor of an inorganic porous support capable of further improving purity or the like in an efficient nucleic acid production method, particularly in the production of a nucleic acid; an inorganic porous support; and a method for producing a nucleic acid using the inorganic porous support. The present invention provides: an inorganic porous substrate having silyl groups respectively represented by (i) and (ii) and having the characteristic properties (iii) to (v); an inorganic porous support derived from the inorganic porous substrate; and a method for producing a nucleic acid using the inorganic porous support. (i) A silyl group (A): a silyl group represented by formula (i-1); (ii) a silyl group (B): at least one silyl group selected from the group consisting of silyl groups respectively represented by (ii-1), (ii-2) and (ii-3); (iii) the particle diameter is 1 μm or more; (iv) the pore diameter is 20 nm or more; and (v) the cumulative pore volume in a pore diameter range of 40 to 1000 nm is more than 0.32 mL/g and 4 mL/g or less.
Inventors:
ISHIYAMA TAKESHI (JP)
OSHIRO IKUYA (JP)
HARA TAKASHI (JP)
OSHIRO IKUYA (JP)
HARA TAKASHI (JP)
Application Number:
PCT/JP2021/018075
Publication Date:
November 18, 2021
Filing Date:
May 12, 2021
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
C01B39/36; B01J32/00; C01B33/12; C07F7/18; C07H21/00
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| WO2020202951A1 | 2020-10-08 | |||
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Other References:
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CHAKHMAKHCHEVA: "Protective Groups in the Chemical Synthesis of Oligoribonucleotides", RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, vol. 39, no. 1, 2013, pages 1 - 21, XP035369459, DOI: 10.1134/S1068162013010020
TOSOH RESEARCH & TECHNOLOGY REVIEW, vol. 45, 2001
A.P. GUZAEVM. MANOHARAN, J AM CHEM SOC, vol. 125, 2003, pages 2380 - 2381
R.K. KUMARA.P. GUZAEVC. RENTELV.T RAVIKUMAR, TETRAHEDRON, vol. 62, 2006, pages 4528
"Concise Encyclopedia Of Polymer Science And Engineering", 1990, JOHN WILEY & SONS, pages: 858 - 859
ENGLISCH ET AL.: "Angewandte Chemie", vol. 30, 1991, INTERNATIONAL EDITION, pages: 613
CHAKHMAKHCHEVA: "Protective Groups in the Chemical Synthesis of Oligoribonucleotides", RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, vol. 39, no. 1, 2013, pages 1 - 21, XP035369459, DOI: 10.1134/S1068162013010020
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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