Title:
IMPROVING SIGNAL TO NOISE IN IMMUNOASSAYS
Document Type and Number:
WIPO Patent Application WO/2024/059707
Kind Code:
A3
Abstract:
The present disclosure includes certain steps in immunoassays, such as immunoassays based on chemiluminescence, which increase assay sensitivity as based on a variety of metrics including increasing signal to noise and decreasing limits of detection. One strategy for these enhancements involves movement, and potential sequestration, of solid phases in one triggering reagent prior to addition of a second triggering reagent for chemiluminescence..
Inventors:
MITRA NIVEDITA (IN)
V M RAMYA (IN)
AZHAR MOHIUDEEN (IN)
JIANG QINGPING (US)
CHAKRABORTY ISHITA (IN)
SHARPE DAVID (US)
V M RAMYA (IN)
AZHAR MOHIUDEEN (IN)
JIANG QINGPING (US)
CHAKRABORTY ISHITA (IN)
SHARPE DAVID (US)
Application Number:
PCT/US2023/074184
Publication Date:
April 25, 2024
Filing Date:
September 14, 2023
Export Citation:
Assignee:
SIEMENS HEALTHCARE DIAGNOSTICS INC (US)
International Classes:
B03C1/02; B03C1/28; C12N15/10; G01N33/543
Attorney, Agent or Firm:
KRENICKY, Michael W. et al. (US)
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