Title:
HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN
Document Type and Number:
WIPO Patent Application WO/2023/205463
Kind Code:
A8
Abstract:
Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
Inventors:
MILLER MARK (US)
HURLEY DENNIS (US)
NEUBERT TIMOTHY (US)
ARUMUGAM VIJAYALAKSMI (US)
HADIDA RUAH SARA (US)
MCCARTNEY JASON (US)
ZHOU JINGLAN (US)
CHAU JACLYN (US)
DEMORET ROBERT (US)
GHIRMAI SENAIT (US)
VALIULIN ROMAN (US)
KINTZER ALEXANDER (US)
SLOCHOWER DAVID (US)
AERTGEERTS KATHLEEN (US)
BECK ELIZABETH (US)
MUI JAMES (US)
WRIGHT MIRANDA (US)
KNEGTEL RONALD (US)
CHUDYK EWA (US)
PINDER JOANNE (US)
DODD JAMES (US)
SIMPSON IAIN (US)
HURLEY DENNIS (US)
NEUBERT TIMOTHY (US)
ARUMUGAM VIJAYALAKSMI (US)
HADIDA RUAH SARA (US)
MCCARTNEY JASON (US)
ZHOU JINGLAN (US)
CHAU JACLYN (US)
DEMORET ROBERT (US)
GHIRMAI SENAIT (US)
VALIULIN ROMAN (US)
KINTZER ALEXANDER (US)
SLOCHOWER DAVID (US)
AERTGEERTS KATHLEEN (US)
BECK ELIZABETH (US)
MUI JAMES (US)
WRIGHT MIRANDA (US)
KNEGTEL RONALD (US)
CHUDYK EWA (US)
PINDER JOANNE (US)
DODD JAMES (US)
SIMPSON IAIN (US)
Application Number:
PCT/US2023/019469
Publication Date:
March 28, 2024
Filing Date:
April 21, 2023
Export Citation:
Assignee:
VERTEX PHARMA (US)
International Classes:
A61P9/06; A61K31/4375; A61K31/4709; A61K31/496; A61K31/4985; A61K31/506; A61K31/517; A61K31/541; A61K31/55; A61K31/553; A61P25/02; A61P29/00; C07D215/233; C07D239/91; C07D401/04; C07D401/14; C07D405/14; C07D471/04; C07D519/00
Attorney, Agent or Firm:
STURLIS, Steven et al. (US)
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