Title:
GENE EDITING TO IMPROVE JOINT FUNCTION
Document Type and Number:
WIPO Patent Application WO/2023/288135
Kind Code:
A3
Abstract:
Treatment of osteoarthritis, degenerative joint disease, and other joint dysfunction is complex and there are few long term options for either symptomatic relief or restoring joint function. The present disclosure provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritis and to treat osteoarthritis and other arthritis in a mammalian joint.
Inventors:
GENTSCH GEORGE (GB)
MILLETT PETER J (US)
RUSSELL IAIN ALASDAIR (GB)
ALLEN MATTHEW J (GB)
MILLETT PETER J (US)
RUSSELL IAIN ALASDAIR (GB)
ALLEN MATTHEW J (GB)
Application Number:
PCT/US2022/037490
Publication Date:
February 23, 2023
Filing Date:
July 18, 2022
Export Citation:
Assignee:
ORTHOBIO THERAPEUTICS INC (US)
GENTSCH GEORGE (GB)
GENTSCH GEORGE (GB)
International Classes:
A61K48/00; C12N9/22; C12N15/11; C12N15/113; A61K35/76; C12N15/86
Domestic Patent References:
| WO2017083722A1 | 2017-05-18 |
Foreign References:
| US20200360454A1 | 2020-11-19 | |||
| US20050282198A1 | 2005-12-22 |
Attorney, Agent or Firm:
ANTCZAK, Andrew J. et al. (US)
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