Title:
FOUR ENGINEERING YEASTS CAPABLE OF EFFICIENTLY SYNTHESIZING INTERMEDIATE PRODUCT OR END PRODUCT IN SYNTHETIC ROUTE OF GINSENOSIDE RO AND METHOD
Document Type and Number:
WIPO Patent Application WO/2023/103365
Kind Code:
A1
Abstract:
Provided are four engineering yeasts, which are respectively engineering yeast CE-P1 capable of synthesizing calenduloside E, with a deposit number of CGMCC No. 23731, engineering yeast IVA-P1 capable of synthesizing chikusetsusaponin IVa, with a deposit number of CGMCC No. 23732, engineering yeast R1-P1 capable of synthesizing zingibroside R1, with a deposit number of CGMCC No. 23733, and engineering yeast Ro-P1 capable of synthesizing ginsenoside Ro, with a deposit number of CGMCC No. 23734. The de novo synthesis of a target compound is achieved by means of the above-mentioned engineering yeasts.
Inventors:
FENG XUDONG (CN)
REN SHICHAO (CN)
LI CHUN (CN)
SUN QIUYAN (CN)
REN SHICHAO (CN)
LI CHUN (CN)
SUN QIUYAN (CN)
Application Number:
PCT/CN2022/104358
Publication Date:
June 15, 2023
Filing Date:
July 07, 2022
Export Citation:
Assignee:
BEIJING INSTITUTE TECH (CN)
International Classes:
C12N1/19; C12N15/56; C12P33/20; C12R1/865
Foreign References:
| CN114134060A | 2022-03-04 | |||
| CN110950922A | 2020-04-03 | |||
| CN105535003A | 2016-05-04 |
Other References:
DATABASE Nucleotide 14 March 2022 (2022-03-14), ANONYMOUS : "Panax notoginseng cellulose synthase-like M (CSLM1) mRNA, complete cds", XP093071776, retrieved from NCBI Database accession no. OM641784.1
DATABASE Protein 27 June 2016 (2016-06-27), ANONYMOUS : "PREDICTED: cellulose synthase-like protein G2 [Daucus carota subsp. sativus]", XP093071780, retrieved from NCBI Database accession no. XP_017237622.1
DATABASE Protein 27 June 2016 (2016-06-27), ANONYMOUS : "PREDICTED: cellulose synthase-like protein G2 [Daucus carota subsp. sativus]", XP093071780, retrieved from NCBI Database accession no. XP_017237622.1
Attorney, Agent or Firm:
HAIHONG JIACHENG INTELLECTUAL PROPERTY & PARTNERS (CN)
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