Title:
EXOSOME FOR PREVENTING OR TREATING TUMORS, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/071924
Kind Code:
A1
Abstract:
In one embodiment of the present invention, the present invention relates to an exosome and uses thereof, the exosome comprising a protein that induces cell death and a polypeptide that increases the half-life of an exosome. The exosome of the present invention has a longer retention period in the body than an exosome not comprising the polypeptide, and have the excellent effect of delivering a protein that induces cell death to tumor tissue, and thus can be used as an agent for tumor treatment.
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Inventors:
KIM EUNHEE (KR)
HAN JEONG-HOON (KR)
NAM SUJIN (KR)
HAN JEONG-HOON (KR)
NAM SUJIN (KR)
Application Number:
PCT/KR2023/014698
Publication Date:
April 04, 2024
Filing Date:
September 25, 2023
Export Citation:
Assignee:
KAINOS MEDICINE INC (KR)
International Classes:
C12N15/85; A61K38/17; A61K47/46; A61P35/00; C07K14/47; C07K14/71; C12N9/26
Domestic Patent References:
| WO1996040864A1 | 1996-12-19 |
Foreign References:
| KR102129067B1 | 2020-07-08 |
Other References:
PARK GYEONGRIN, KIM BOK-SEOK, KIM EUNHEE: "A novel function of FAF1, which induces dopaminergic neuronal death through cell-to-cell transmission", CELL COMMUNICATION AND SIGNALING, vol. 18, no. 1, 1 December 2020 (2020-12-01), XP055973667, DOI: 10.1186/s12964-020-00632-8
YEOM KYUNG MUN, KIM SO UN, WOO MUN YOUNG, NOH JUN HONG, IM SANG HYUK: "Recent Progress in Metal Halide Perovskite‐Based Tandem Solar Cells", ADVANCED MATERIALS, VCH PUBLISHERS, DE, vol. 32, no. 51, 1 December 2020 (2020-12-01), DE , XP093118783, ISSN: 0935-9648, DOI: 10.1002/adma.202002228
DATABASE Protein ANONYMOUS : "FAS-associated factor 1 [Homo sapiens] ", XP093151263, retrieved from NCBI
YEOM KYUNG MUN, KIM SO UN, WOO MUN YOUNG, NOH JUN HONG, IM SANG HYUK: "Recent Progress in Metal Halide Perovskite‐Based Tandem Solar Cells", ADVANCED MATERIALS, VCH PUBLISHERS, DE, vol. 32, no. 51, 1 December 2020 (2020-12-01), DE , XP093118783, ISSN: 0935-9648, DOI: 10.1002/adma.202002228
DATABASE Protein ANONYMOUS : "FAS-associated factor 1 [Homo sapiens] ", XP093151263, retrieved from NCBI
Attorney, Agent or Firm:
FIRSTLAW P.C. (KR)
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