Title:
COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERCHOLESTEROLEMIA AND/OR CARDIOVASCULAR DISEASE
Document Type and Number:
WIPO Patent Application WO/2024/061296
Kind Code:
A2
Abstract:
Compositions and methods are described herein for treating subjects having hypercholesterolemia and/or cardiovascular disease.
Inventors:
SHI FUXIN (US)
CAO WENHU (CN)
CHEN YE (CN)
LIU HUANLE (CN)
QIU HAN (CN)
LIAO LEQI (CN)
CAO WENHU (CN)
CHEN YE (CN)
LIU HUANLE (CN)
QIU HAN (CN)
LIAO LEQI (CN)
Application Number:
PCT/CN2023/120234
Publication Date:
March 28, 2024
Filing Date:
September 21, 2023
Export Citation:
Assignee:
ACCUREDIT THERAPEUTICS SUZHOU CO LTD (CN)
International Classes:
C12N15/113
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| WO2020198697A1 | 2020-10-01 | |||
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Other References:
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VESTERWENGEL, BIOCHEMISTRY, vol. 43, no. 42, 2004, pages 13233 - 41
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SHMAKOV ET AL., MOLECULAR CELL, vol. 60, 2015, pages 385 - 397
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MAKAROVA ET AL., NAT. REV. MICROBIOL., vol. 9, 2011, pages 467 - 477
MAKAROVA ET AL., NAT. REV. MICROBIOL, vol. 13, 2015, pages 722 - 36
SCHMIDT ET AL., NATURE METHODS, vol. 4, 2007, pages 1051 - 1057
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COOPER GR ET AL.: "Blood lipid measurements. Variations and practical utility", JAMA, vol. 267, no. 12, 25 March 1992 (1992-03-25), pages 1652 - 60
SAMBROOK: "Molecular Cloning: A Laboratory Manual", 1989
GAIT, OLIGONUCLEOTIDE SYNTHESIS, 1984
FRESHNEY, ANIMAL CELL CULTURE, 1987
METHODS IN ENZYMOLOGY: "Handbook of Experimental Immunology", 1996
TSAI ET AL., NATURE BIOTECHNOLOGY, vol. 33, 2015, pages 187 - 197
VESTERWENGEL, BIOCHEMISTRY, vol. 43, no. 42, 2004, pages 13233 - 41
ZETSCHE ET AL., CELL, vol. 163, 2015, pages 1 - 13
MAKAROVA ET AL., NAT REV MICROBIOL, vol. 13, no. 11, 2015, pages 722 - 36
SHMAKOV ET AL., MOLECULAR CELL, vol. 60, 2015, pages 385 - 397
DU F ET AL.: "Novel domain interaction regulates secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein", J BIOL CHEM., vol. 286, no. 50, 16 December 2011 (2011-12-16), pages 43054 - 61, XP055061701, DOI: 10.1074/jbc.M111.273474
MAKAROVA ET AL., NAT. REV. MICROBIOL., vol. 9, 2011, pages 467 - 477
MAKAROVA ET AL., NAT. REV. MICROBIOL, vol. 13, 2015, pages 722 - 36
SCHMIDT ET AL., NATURE METHODS, vol. 4, 2007, pages 1051 - 1057
SHENDURE ET AL., NATURE, vol. 26, 2008, pages 1135 - 1145
COOPER GR ET AL.: "Blood lipid measurements. Variations and practical utility", JAMA, vol. 267, no. 12, 25 March 1992 (1992-03-25), pages 1652 - 60
SAMBROOK: "Molecular Cloning: A Laboratory Manual", 1989
GAIT, OLIGONUCLEOTIDE SYNTHESIS, 1984
FRESHNEY, ANIMAL CELL CULTURE, 1987
METHODS IN ENZYMOLOGY: "Handbook of Experimental Immunology", 1996
TSAI ET AL., NATURE BIOTECHNOLOGY, vol. 33, 2015, pages 187 - 197
Attorney, Agent or Firm:
BEIJING YINGKE LAW FIRM (CN)
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