Title:
COMPOSITION CONTAINING PEPTIDE COMPOUND FOR USE WITH SURFACTANT
Document Type and Number:
WIPO Patent Application WO/2023/214509
Kind Code:
A1
Abstract:
The present invention relates to a composition containing the following (1) for use with the following (2). (1) At least one peptide compound selected from the group consisting of the following (i), (ii) and (iii): (i) a peptide compound containing one or more N-substituted amino acid residues; (ii) a peptide compound having a ClogP of 4-25 inclusive; and (iii) a peptide compound having a solubility in a 50 mM phosphate buffer solution (pH 6.5) of 10 mg/mL or less at 37°C and 1 atm. (2) At least one surfactant selected from the group consisting of the following (iv) and (v): (iv) a surfactant having a straight-chain alkylene structure, said alkylene structure having 5-13 inclusive carbon atoms; and (v) a surfactant having a carnitine residue.
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Inventors:
NAKAE SHINICHI (JP)
TAKANO RYUSUKE (JP)
TANG HENGMIN (JP)
SAKURAI YUJI (JP)
TAKANO RYUSUKE (JP)
TANG HENGMIN (JP)
SAKURAI YUJI (JP)
Application Number:
PCT/JP2023/015658
Publication Date:
November 09, 2023
Filing Date:
April 19, 2023
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K38/12; A61K9/08; A61K38/00; A61K47/12; A61K47/14; A61K47/18; A61K47/20
Domestic Patent References:
| WO2021090855A1 | 2021-05-14 | |||
| WO2018225864A1 | 2018-12-13 | |||
| WO2018225851A1 | 2018-12-13 | |||
| WO2013100132A1 | 2013-07-04 | |||
| WO2018225864A1 | 2018-12-13 | |||
| WO2021090855A1 | 2021-05-14 | |||
| WO2021090855A1 | 2021-05-14 |
Foreign References:
| JP2014518213A | 2014-07-28 | |||
| JP2015529684A | 2015-10-08 | |||
| JP2009518437A | 2009-05-07 | |||
| JP2009518437W |
Other References:
TSUCHIYA, AKEMI ET AL.: "Can a tacrolimus-cyclosporin injection be administered accurately? - Examination of errors when administering using an infusion pump.", TRANSPLANTATION NOW, NIHON IGAKUKAN, JP, vol. 13, no. 2, 1 January 2000 (2000-01-01), JP , pages 173 - 175, XP009545422, ISSN: 0916-0094
CLOGP REFERENCE MANUAL DAYLIGHT VERSION 4.9, 1 August 2011 (2011-08-01), Retrieved from the Internet
"Daylight Version 4.95", 1 August 2011, DAYLIGHT CHEMICAL INFORMATION SYSTEMS, INC.
CLOGP REFERENCE MANUAL DAYLIGHT VERSION 4.9, 1 August 2011 (2011-08-01), Retrieved from the Internet
"Daylight Version 4.95", 1 August 2011, DAYLIGHT CHEMICAL INFORMATION SYSTEMS, INC.
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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