Title:
BONE REGENERATION COMPOSITION AND DOSAGE FORM
Document Type and Number:
WIPO Patent Application WO/2023/191176
Kind Code:
A1
Abstract:
The present invention relates to a bone regeneration composition comprising collagen, thrombin, and albumin, a therapeutic use using same, and a dosage form. The composition and the dosage form, according to the present invention, may not only activate undifferentiated cells in bone marrow but also may activate a bone regeneration capacity in bone marrow through the activation and differentiation of osteoclasts and osteoblasts. Accordingly, the present invention may be usefully employed for treatment of a state of requiring bone regeneration, for example, a disease caused by a defect in bone remodeling, especially, bisphosphonate-related osteonecrosis of the jaws.
Inventors:
KWON KYUNG HWAN (KR)
Application Number:
PCT/KR2022/005991
Publication Date:
October 05, 2023
Filing Date:
April 27, 2022
Export Citation:
Assignee:
DENHOUSE CO LTD (KR)
International Classes:
A61K38/39; A61K31/167; A61K38/38; A61K38/48; A61L27/22; A61L27/24; A61L27/36; A61L27/54; A61P19/08
Domestic Patent References:
| WO2000040277A1 | 2000-07-13 |
Foreign References:
| KR102273121B1 | 2021-07-06 | |||
| KR20110000485A | 2011-01-03 | |||
| KR20120046430A | 2012-05-10 |
Other References:
KATARIVAS LEVY GALIT, ONG JOHN, BIRCH MARK A., JUSTIN ALEXANDER W., MARKAKI ATHINA E.: "Albumin-Enriched Fibrin Hydrogel Embedded in Active Ferromagnetic Networks Improves Osteoblast Differentiation and Vascular Self-Organisation", POLYMERS, vol. 11, no. 11, pages 1743, XP093094056, DOI: 10.3390/polym11111743
Attorney, Agent or Firm:
GURU IP LAW FIRM (KR)
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