Title:
BLOCK COPOLYMER AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2021/172559
Kind Code:
A1
Abstract:
This copolymer contains a hydroxycarboxylic acid (A) having a hydroxy group only at the 2-position and a hydroxycarboxylic acid (B) having a hydroxy group at a position other than the 2-position, and has a homopolymerized segment composed of one hydroxycarboxylic acid selected from the group consisting of the hydroxycarboxylic acid (A) and the hydroxycarboxylic acid (B) and a copolymerized segment containing at least 2 hydroxycarboxylic acids selected from the group consisting of the hydroxycarboxylic acid (A) and the hydroxycarboxylic acid (B).
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Inventors:
MATSUMOTO KENICHIRO (JP)
FUKUI TOSHIAKI (JP)
ISHIHARA SHIZURU (JP)
FUKUI TOSHIAKI (JP)
ISHIHARA SHIZURU (JP)
Application Number:
PCT/JP2021/007499
Publication Date:
September 02, 2021
Filing Date:
February 26, 2021
Export Citation:
Assignee:
UNIV HOKKAIDO NAT UNIV CORP (JP)
International Classes:
C12P7/62; C08G63/06
Domestic Patent References:
| WO2007049716A1 | 2007-05-03 |
Other References:
MATSUMOTO KEN’ICHIRO, HORI CHIAKI, FUJII RYUNOSUKE, TAKAYA MASAHIRO, OOBA TAKASHI, OOI TOSHIHIKO, ISONO TAKUYA, SATOH TOSHIFUMI, T: "Dynamic Changes of Intracellular Monomer Levels Regulate Block Sequence of Polyhydroxyalkanoates in Engineered Escherichia coli", BIOMACROMOLECULES, vol. 19, no. 2, 12 February 2018 (2018-02-12), US, pages 662 - 671, XP055850465, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.7b01768
MATSUMOTO, KENICHIRO: "Development on Biosynthesis of sequence-regulated polyesters", BAIOSAIENSU TO INDASUTORI - BIOSCIENCE TO INDUSTRY, vol. 77, no. 3, 10 May 2019 (2019-05-10), JP, pages 252 - 253, XP009530593, ISSN: 0914-8981
SUN, J. ET AL.: "Production of P(3- hydroxybutyrate-co-3-hydroxyhexanoate-co-3- hydroxyoctanoate) terpolymers using a chimeric PHA synthase in recombinant Ralstonia eutropha and Pseudomonas putida", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 74, no. 8, 7 August 2010 (2010-08-07), pages 1716 - 1718, XP055358664, DOI: 10.1271/bbb.100242
ARAI, S. ET AL.: "Biosynthesis of Random-Homo Block Copolymer Poly [Glycolate-ran-3- Hydroxybutyrate (3HB)]-b-Poly(3HB) Using Sequence- Regulating Chimeric Polyhydroxyalkanoate Synthase in Escherichia coli", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 8, no. 612991, 8 December 2020 (2020-12-08), pages 1 - 10, XP055850473
MENG DE-CHUAN, CHEN GUO-QIANG: "Synthetic Biology of Polyhydroxyalkanoates (PHA", ADVANCES IN BIOCHEMICAL ENGINEERING/BIOTECHNOLOGY, vol. 162, 2018, DE, pages 147 - 174, XP009530595, ISSN: 0724-6145, DOI: 10.1007/10_2017_3
MATSUMOTO ET AL., APPL. MICROBIOL. BIOTECHNOL, vol. 97, 2013, pages 8011
MATSUMOTO K ET AL., BIOMACROMOLECULES, vol. 19, no. 2, 2018, pages 662
SUDO M. ET AL., J BIOSCI BIOENG, vol. 30785-6, no. 19, 18 October 2019 (2019-10-18), pages 1389 - 1723
SOUTHERN, E. M, MOL. BIOL., vol. 98, 1975, pages 503
SAIKI, R. K. ET AL., SCIENCE, vol. 230, 1985, pages 1350 - 1354
SAIKI, R.K. ET AL., SCIENCE, vol. 239, 1988, pages 487 - 491
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 2264 - 2268
KARLINALTSCHUL, PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
A. E. HOFMEISTER ET AL., EUR. J. BIOCHEM., vol. 206, pages 547 - 552
WANG ET AL., APPL ENVIRON MICROBIOL., vol. 78, no. 2, January 2012 (2012-01-01), pages 519 - 527
MATSUMOTO K. ET AL., BIOMACROMOLECULES, vol. 10, no. 4, 13 April 2009 (2009-04-13), pages 682 - 685
SCHAFER ET AL., GENE, vol. 145, 1994, pages 69 - 73
QUANDT, J.HYNES, M. P., GENE, vol. 17, 1993, pages 15 - 21
TAGUCHI,S ET AL., PROC. NATL. ACAD. SCI. U.S A., vol. 105, no. 45, 2008, pages 17323 - 17327
MATSUMOTO K. ET AL., ACS BIOMATERIALS SCIENCE & ENGINEERING, vol. 3, no. 12, 2017, pages 3058
JOURNAL OF BIOTECHNOLOGY, vol. 152, 2011, pages 144 - 146
LETTERS IN APPLIED MICROBIOLOGY, vol. 25, 1997, pages 371 - 374
ZHANG ET AL., MICROBIAL CELL FACTORIES, vol. 18, no. 147, 2019
PNAS, vol. 105, no. 45, 11 November 2008 (2008-11-11), pages 17323 - 17327
MATSUMOTO, KENICHIRO: "Development on Biosynthesis of sequence-regulated polyesters", BAIOSAIENSU TO INDASUTORI - BIOSCIENCE TO INDUSTRY, vol. 77, no. 3, 10 May 2019 (2019-05-10), JP, pages 252 - 253, XP009530593, ISSN: 0914-8981
SUN, J. ET AL.: "Production of P(3- hydroxybutyrate-co-3-hydroxyhexanoate-co-3- hydroxyoctanoate) terpolymers using a chimeric PHA synthase in recombinant Ralstonia eutropha and Pseudomonas putida", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 74, no. 8, 7 August 2010 (2010-08-07), pages 1716 - 1718, XP055358664, DOI: 10.1271/bbb.100242
ARAI, S. ET AL.: "Biosynthesis of Random-Homo Block Copolymer Poly [Glycolate-ran-3- Hydroxybutyrate (3HB)]-b-Poly(3HB) Using Sequence- Regulating Chimeric Polyhydroxyalkanoate Synthase in Escherichia coli", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 8, no. 612991, 8 December 2020 (2020-12-08), pages 1 - 10, XP055850473
MENG DE-CHUAN, CHEN GUO-QIANG: "Synthetic Biology of Polyhydroxyalkanoates (PHA", ADVANCES IN BIOCHEMICAL ENGINEERING/BIOTECHNOLOGY, vol. 162, 2018, DE, pages 147 - 174, XP009530595, ISSN: 0724-6145, DOI: 10.1007/10_2017_3
MATSUMOTO ET AL., APPL. MICROBIOL. BIOTECHNOL, vol. 97, 2013, pages 8011
MATSUMOTO K ET AL., BIOMACROMOLECULES, vol. 19, no. 2, 2018, pages 662
SUDO M. ET AL., J BIOSCI BIOENG, vol. 30785-6, no. 19, 18 October 2019 (2019-10-18), pages 1389 - 1723
SOUTHERN, E. M, MOL. BIOL., vol. 98, 1975, pages 503
SAIKI, R. K. ET AL., SCIENCE, vol. 230, 1985, pages 1350 - 1354
SAIKI, R.K. ET AL., SCIENCE, vol. 239, 1988, pages 487 - 491
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 2264 - 2268
KARLINALTSCHUL, PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
A. E. HOFMEISTER ET AL., EUR. J. BIOCHEM., vol. 206, pages 547 - 552
WANG ET AL., APPL ENVIRON MICROBIOL., vol. 78, no. 2, January 2012 (2012-01-01), pages 519 - 527
MATSUMOTO K. ET AL., BIOMACROMOLECULES, vol. 10, no. 4, 13 April 2009 (2009-04-13), pages 682 - 685
SCHAFER ET AL., GENE, vol. 145, 1994, pages 69 - 73
QUANDT, J.HYNES, M. P., GENE, vol. 17, 1993, pages 15 - 21
TAGUCHI,S ET AL., PROC. NATL. ACAD. SCI. U.S A., vol. 105, no. 45, 2008, pages 17323 - 17327
MATSUMOTO K. ET AL., ACS BIOMATERIALS SCIENCE & ENGINEERING, vol. 3, no. 12, 2017, pages 3058
JOURNAL OF BIOTECHNOLOGY, vol. 152, 2011, pages 144 - 146
LETTERS IN APPLIED MICROBIOLOGY, vol. 25, 1997, pages 371 - 374
ZHANG ET AL., MICROBIAL CELL FACTORIES, vol. 18, no. 147, 2019
PNAS, vol. 105, no. 45, 11 November 2008 (2008-11-11), pages 17323 - 17327
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CENTCREST IP ATTORNEYS (JP)
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