Title:
BISPECIFIC CHIMERIC ANTIGEN RECEPTOR TARGETING CD19 AND CD22
Document Type and Number:
WIPO Patent Application WO/2024/082178
Kind Code:
A1
Abstract:
Provided is a chimeric antigen receptor, comprising a first antigen-binding domain and a second antigen-binding domain, wherein the first antigen-binding domain targets CD19, and the second antigen-binding domain targets CD22. Also provided are a cell comprising the chimeric antigen receptor, and preparation methods for and uses of the chimeric antigen receptor and the cell.
Inventors:
LIAO XUEMEI (CN)
CHEN ZHUO (CN)
XIE MANMAN (CN)
CHENG XIAOCUI (CN)
LIU YANG (CN)
MA MINGROU (CN)
PU QUJIN (CN)
LIU TINGTING (CN)
XIA GUANGXIN (CN)
KE YING (CN)
CHEN ZHUO (CN)
XIE MANMAN (CN)
CHENG XIAOCUI (CN)
LIU YANG (CN)
MA MINGROU (CN)
PU QUJIN (CN)
LIU TINGTING (CN)
XIA GUANGXIN (CN)
KE YING (CN)
Application Number:
PCT/CN2022/126207
Publication Date:
April 25, 2024
Filing Date:
October 19, 2022
Export Citation:
Assignee:
SHANGHAI PHARMACEUTICALS HOLDING CO LTD (CN)
International Classes:
C07K14/705; A61K39/00; A61P35/00; C12N5/071; C12N15/12; C12N15/62; C12N15/63; G01N33/50
Foreign References:
| CN114478803A | 2022-05-13 | |||
| CN112195157A | 2021-01-08 | |||
| CN113493516A | 2021-10-12 | |||
| CN110938148A | 2020-03-31 | |||
| CN107383196A | 2017-11-24 |
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
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