Title:
BIOMARKER FOR LIVER CANCER DIAGNOSIS AND ARTIFICIAL INTELLIGENCE-BASED INFORMATION PROVISION METHOD FOR LIVER CANCER DIAGNOSIS
Document Type and Number:
WIPO Patent Application WO/2024/085447
Kind Code:
A1
Abstract:
The present invention relates to a biomarker for liver cancer diagnosis and an artificial intelligence-based method for providing information for liver cancer diagnosis. More specifically, the present invention relates to a biomarker composition for liver cancer diagnosis, comprising histidine-rich glycoprotein (HRG), osteopontin (OPN), complement component C7 (C7), and alpha-fetoprotein (AFP), and an artificial intelligence-based method for providing information for liver cancer diagnosis using the biomarker. As a result of establishing an artificial intelligence-based algorithm model for liver cancer diagnosis by using the biomarker for liver cancer diagnosis selected in the present invention, it was found that the liver cancer screening capability has a sensitivity of 76.25% and a specificity of 95.83%, which confirms a much higher accuracy compared to existing liver cancer screening methods. Therefore, the present invention can effectively provide information for liver cancer diagnosis.
Inventors:
KIM SEUNG KU (KR)
KIM KI TAE (KR)
KIM KI TAE (KR)
Application Number:
PCT/KR2023/013630
Publication Date:
April 25, 2024
Filing Date:
September 12, 2023
Export Citation:
Assignee:
INNOBATION BIO CO LTD (KR)
International Classes:
G01N33/574; G16B25/00; G16B40/00
Foreign References:
KR102421471B1 | 2022-07-18 | |||
US20140235494A1 | 2014-08-21 | |||
KR20180123978A | 2018-11-20 | |||
US20210208147A1 | 2021-07-08 | |||
US20150095069A1 | 2015-04-02 |
Attorney, Agent or Firm:
PADO IP LAW PLLC (KR)
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