APPARATUS AND SYSTEM FOR PARTICLE MANIPULATION

WIPO Patent Application WO/2023/065063

A1

An apparatus and a method for capturing and manipulating particles, relating to the field of acoustic manipulation. In view of the problems in the prior art that can't achieve a contactless, versatile, selective, and universal manipulation method for particles, the method provides photoacoustic tweezers, which uses a photoacoustic transducer unit and an electroacoustic transducer unit to form a bimodal transducer, generates a weak acoustic wave and strong acoustic wave respectively through signal excitation. The strong acoustic wave behaving as a gain medium, amplifies the acoustic radiation force of the weak acoustic wave. The method enables contactless and label-free selective capture and manipulation of particles. Further, the amplified acoustic radiation force enhances biocompatibility by requiring lower optical powers than alternative optical methods. The method can be used to manipulate multiple particles with different sizes ranging from 1 μm to 1 mm at the same time, which have capability of particle assembly. The method permits adjustment of dynamically reconfigurable acoustic field with high versatility. Furthermore, the direction of the acoustic radiation force can be reversed by adjusting the phase difference, causing the behavior of repelling and attracting particles.

WANG QING (CN)
RIAUD ANTOINE JEAN-PIERRE RENE (CN)
ZHOU JIA (CN)

PCT/CN2021/124322

April 27, 2023

October 18, 2021

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UNIV FUDAN (CN)

B01J19/10

WO2015134831A1	2015-09-11
WO2010123453A1	2010-10-28
WO2021146698A1	2021-07-22
WO2013116311A1	2013-08-08

US20200338593A1

2020-10-29

RAYTO PARTNERS, P.C. (CN)

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