Title:
ANTIBODY SPECIFICALLY BINDING TO V5 EXON OF CD44, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/093147
Kind Code:
A1
Abstract:
The present invention relates to an antibody specifically binding to the v5 exon of human CD44 or a fragment thereof. The present invention also relates to a chimeric antigen receptor molecule comprising the antibody or the fragment thereof, a nucleic acid molecule, a recombinant vector and a cell for encoding the antibody or the fragment thereof and the chimeric antigen receptor molecule, or an antibody-drug conjugate containing the antibody. The present invention further relates to the use of the antibody, the chimeric antigen receptor molecule or the antibody-drug conjugate.
Inventors:
SHEN PINGPING (CN)
BEI YUNCHENG (CN)
BEI YUNCHENG (CN)
Application Number:
PCT/CN2023/087794
Publication Date:
May 10, 2024
Filing Date:
April 12, 2023
Export Citation:
Assignee:
MACERA THERAPEUTICS (CN)
International Classes:
C07K16/28; A61K39/395; A61P35/00; C07K19/00; C12N5/10; C12N15/09; C12N15/13
Domestic Patent References:
| WO2005007700A1 | 2005-01-27 | |||
| WO1995004547A1 | 1995-02-16 |
Foreign References:
| CN106061496A | 2016-10-26 | |||
| US20030108984A1 | 2003-06-12 | |||
| KR20150142306A | 2015-12-22 | |||
| CN101605812A | 2009-12-16 | |||
| CN110776559A | 2020-02-11 | |||
| US20030190319A1 | 2003-10-09 |
Attorney, Agent or Firm:
IPSUNNY (CN)
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