ANTIBODY FUSION PROTEIN AND PREPARATION AND USE THEREOF - BEIJING INNOCARE PHARMA TECH CO LTD

Title:

ANTIBODY FUSION PROTEIN AND PREPARATION AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/083226

Kind Code:

A1

Abstract:

An activatable antibody fusion protein, said fusion protein comprising an antibody portion specifically binding to a target, an immunoglobulin Fc portion, a masking portion and a cytokine portion. The present invention further relates to a preparation method for the fusion protein and the use of same in treatment and/or prevention of tumors.

Inventors:

OUYANG XUESONG (CN)
WANG XIAOYAN (CN)
ZHANG HONGJUAN (CN)

Application Number:

PCT/CN2023/125682

Publication Date:

April 25, 2024

Filing Date:

October 20, 2023

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Assignee:

BEIJING INNOCARE PHARMA TECH CO LTD (CN)

International Classes:

C07K19/00; A61K47/68; A61P35/00; A61P37/04; C07K14/52; C07K14/54; C07K14/55; C07K16/28; C07K16/30; C12N15/13

Attorney, Agent or Firm:

CHINA PATENT AGENT (H.K.) LTD. (CN)

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