Title:
AMMONIA METABOLISM PROMOTER
Document Type and Number:
WIPO Patent Application WO/2018/225482
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a material which has an excellent ammonia metabolism improving effect and is effective for endurance improvement, fatigue resistance, etc. This ammonia metabolism promoter has catechins and ornithine as active ingredients. This endurance improving agent has catechins and ornithine as active ingredients. This anti-fatigue agent has catechins and ornithine as active ingredients. This agent for suppressing reduction in blood sugar levels during exercise has catechins and ornithine as active ingredients. This agent for promoting the recovery from reduced blood sugar levels due to exercise has catechins and ornithine as active ingredients. This agent for suppressing the reduction of muscle glycogen due to exercise has catechins and ornithine as active ingredients. This muscle endurance improving agent has catechins and ornithine as active ingredients. This agent for preventing or improving hyperammonemia, hepatic encephalopathy, and chronic fatigue syndrome has catechins and ornithine as active ingredients.
Inventors:
HASUMURA TAKAHIRO (JP)
CHIN SHU (JP)
OTA NORIYASU (JP)
MINEGISHI YOSHIHIKO (JP)
OTSUKA ATSUKO (JP)
KOBAYASHI AKEMI (JP)
CHIN SHU (JP)
OTA NORIYASU (JP)
MINEGISHI YOSHIHIKO (JP)
OTSUKA ATSUKO (JP)
KOBAYASHI AKEMI (JP)
Application Number:
PCT/JP2018/019341
Publication Date:
December 13, 2018
Filing Date:
May 18, 2018
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
A61K31/198; A23L33/105; A23L33/17; A61K31/353; A61K36/82; A61P1/16; A61P3/00; A61P43/00; A23F3/16; A61K127/00; C07D311/62
Domestic Patent References:
| WO2007040244A1 | 2007-04-12 | |||
| WO2007142286A1 | 2007-12-13 | |||
| WO2009048148A1 | 2009-04-16 |
Foreign References:
| JPS427767B1 | ||||
| JPS418592B1 | ||||
| JP2000239179A | 2000-09-05 | |||
| JP2012246294A | 2012-12-13 | |||
| JP2011132174A | 2011-07-07 | |||
| JP2013060406A | 2013-04-04 | |||
| JP2005089384A | 2005-04-07 | |||
| JP2008031148A | 2008-02-14 | |||
| JPS59219384A | 1984-12-10 | |||
| JPH0420589A | 1992-01-24 | |||
| JPH05260907A | 1993-10-12 | |||
| JPH05306279A | 1993-11-19 |
Other References:
SACHDEVA, ANAND KAMAL ET AL.: "Epigallocatechin gallate ameliorates behavioral and biochemical deficits in rat model of load-induced chronic fatigue syndrome", BRAIN RESEARCH BULLETIN, vol. 86, 2011, pages 165 - 172, XP028297887
SACHDEVA, ANAND KAMAL ET AL.: "Protective Effect of Epigallocatechin Gallate in Murine Water- Immersion Stress Model of Chronic Fatigue Syndrome", BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY, vol. 106, 2010, pages 490 - 496, XP055554424
SACHDEVA, ANAND KAMAL ET AL.: "Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and biochemical evidence", BEHAVIOURAL BRAIN RESEARCH, vol. 205, no. 2, 2009, pages 414 - 420, XP026673473
TANAKA, MASAAKI ET AL.: "Effects of (-)- epigallocatechin gallate in liver of an animal model of combined(physical and mental) fatigue", NUTRITION, vol. 24, no. 6, May 2008 (2008-05-01), pages 599 - 603, XP022655351
TAKEDA ET AL., J NUTR SCI VITAMINOL, vol. 57, 2011, pages 246 - 250
WALKER, DIABETES, OBESITY AND METABOLISM, vol. 11, 2009, pages 823 - 835
MENEGUELLO ET AL., CELL BIOCHEM FUNCT, vol. 21, 2003, pages 85 - 91
See also references of EP 3636257A4
SACHDEVA, ANAND KAMAL ET AL.: "Protective Effect of Epigallocatechin Gallate in Murine Water- Immersion Stress Model of Chronic Fatigue Syndrome", BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY, vol. 106, 2010, pages 490 - 496, XP055554424
SACHDEVA, ANAND KAMAL ET AL.: "Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and biochemical evidence", BEHAVIOURAL BRAIN RESEARCH, vol. 205, no. 2, 2009, pages 414 - 420, XP026673473
TANAKA, MASAAKI ET AL.: "Effects of (-)- epigallocatechin gallate in liver of an animal model of combined(physical and mental) fatigue", NUTRITION, vol. 24, no. 6, May 2008 (2008-05-01), pages 599 - 603, XP022655351
TAKEDA ET AL., J NUTR SCI VITAMINOL, vol. 57, 2011, pages 246 - 250
WALKER, DIABETES, OBESITY AND METABOLISM, vol. 11, 2009, pages 823 - 835
MENEGUELLO ET AL., CELL BIOCHEM FUNCT, vol. 21, 2003, pages 85 - 91
See also references of EP 3636257A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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