Title:
酵素触媒作用の際にグルタリルアミダーゼの失活を遅らせる方法
Document Type and Number:
Japanese Patent JP4598333
Kind Code:
B2
Abstract:
The present invention relates to a process for delaying the deactivation of glutaryl amidase during enzyme catalysis. The enzyme catalyst is, after maximum conversion of the substrate, separated off by filtration and can be reused in a subsequent reaction batch. In each reaction cycle, the enzyme catalyst loses activity. The inactivation of the enzyme catalyst can be delayed by bringing it into contact with a thiol during the reaction.
Inventors:
Jürgen Bongs
Johannes Maives
Wolfgang Kruse
Claus-Peter Coller
Johannes Maives
Wolfgang Kruse
Claus-Peter Coller
Application Number:
JP2001500800A
Publication Date:
December 15, 2010
Filing Date:
May 13, 2000
Export Citation:
Assignee:
Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung
International Classes:
C12N9/80; C12N9/96; C12N11/08; C12P35/02
Domestic Patent References:
| JP5207879A | ||||
| JP10175980A |
Other References:
J. Basic Microbiol.,1997年,Vol.37,p.403-405
Glutaryl-7-aminocephalosporanic-acid acylase. ,ExPASy Proteomics Server,EC 3.5.1.93,URL,http://kr.expasy.org/enzyme/3.5.1.93
Enzyme and Microbial Technology,1997年,Vol.20,p.368-372
EZIO BATTISTEL,APPLIED BIOTECHEMISTRY AND BIOTECHNOLOGY,1998年 1月 1日,V69 N1,P53-67
Glutaryl-7-aminocephalosporanic-acid acylase. ,ExPASy Proteomics Server,EC 3.5.1.93,URL,http://kr.expasy.org/enzyme/3.5.1.93
Enzyme and Microbial Technology,1997年,Vol.20,p.368-372
EZIO BATTISTEL,APPLIED BIOTECHEMISTRY AND BIOTECHNOLOGY,1998年 1月 1日,V69 N1,P53-67
Attorney, Agent or Firm:
Junji Yuda
Chika Takagi
Kosuke Nishimura
Chika Takagi
Kosuke Nishimura