Title:
シュードモナス・ディミヌタBS-203からのグルタリルセファロスポリンアミダーゼ
Document Type and Number:
Japanese Patent JP2004524006
Kind Code:
A
Abstract:
The invention provides a glutaryl 7-ACA amidase from Pseudomonas diminuta strain BS-203, which catalyzes the hydrolysis of 7-beta-(4-carboxybutanamido)-cephalosporanic acid to 7-aminocephalosporanic acid and glutaric acid. The invention also provides nucleic acid sequences, vectors, and host cells useful in the production of this amidase. The glutaryl 7-ACA amidase can be used for the preparation of 7-aminocephalosporanic acid.
Inventors:
Ross binder
Joan El Hill
Thomas Jay Francesini
William Buoy Barnet Jr.
Michael politino
Suo Win Liu
Shawn M Tonji
Joan El Hill
Thomas Jay Francesini
William Buoy Barnet Jr.
Michael politino
Suo Win Liu
Shawn M Tonji
Application Number:
JP2002529474A
Publication Date:
August 12, 2004
Filing Date:
September 19, 2001
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C12N15/09; C07K14/21; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/80; C12N15/31; C12P35/02; C12R1/38; (IPC1-7): C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/80; C12P35/02
Attorney, Agent or Firm:
Aoyama Aoi
Osamu Kawamiya
Kyousei Tamura
Yushiro Tsuboi
Osamu Kawamiya
Kyousei Tamura
Yushiro Tsuboi